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评估天然产物在皮肤创伤愈合中的治疗干预作用:水豚油的应用。

Evaluation of therapeutic intervention with a natural product in cutaneous wound healing: the use of capybara oil.

机构信息

Laboratory of Ultrastructure and Tecidual Biology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, 20551-030 Rio de Janeiro, RJ, Brazil.

出版信息

Evid Based Complement Alternat Med. 2013;2013:217198. doi: 10.1155/2013/217198. Epub 2013 Jun 10.

Abstract

Capybara oil is commonly used for cutaneous wound healing in traditional South American medicine, although its beneficial effect has never been experimentally proven. The aim of this study was to investigate the effects of the topical application of capybara oil on skin wounds in Swiss mice. The following characteristics of the wounds were observed and evaluated: wound contraction and reepithelialization, the number of polymorphonuclear leukocytes and mast cells, the thickness of the neoepidermis, and the distribution of collagen and elastic fibers. Our study showed that oil extracted from subcutaneous capybara fat was beneficial for wound healing, indicating that capybara oil plays an important role in promoting tissue repair.

摘要

水豚油在南美传统医学中常用于皮肤创伤愈合,尽管其有益效果从未得到实验验证。本研究旨在探讨水豚油局部应用于瑞士小鼠皮肤创伤的效果。观察和评估了以下伤口特征:伤口收缩和再上皮化、多形核白细胞和肥大细胞数量、新生表皮厚度以及胶原和弹性纤维分布。我们的研究表明,从皮下水豚脂肪中提取的油有利于伤口愈合,表明水豚油在促进组织修复中发挥重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9f0/3691902/febb798fa49c/ECAM2013-217198.001.jpg

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