Hietala S O, Silfvenius H, Aasly J, Olivecrona M, Jonsson L
Department of Radiology, University Hospital, Umeå, Sweden.
Eur J Nucl Med. 1990;16(8-10):683-7. doi: 10.1007/BF00998169.
Technetium (99mTc) hexamethyl propylene amine oxime (HM-PAO) was injected into the internal carotid artery in ten epileptic patients after the end of amobarbital speech-memory tests. The cerebral perfusion as visualized from SPET was compared to cerebral angiographies, which showed unilateral filling of intracranial vessels in seven patients. SPET revealed cross-flow between the hemispheres in four of these seven patients. In three patients in whom the angiograms had shown bilateral contrast filling, SPET showed cross-flow in only two. It is concluded that 99mTc-HM-PAO SPET examinations provide valuable information for correct interpretation of amobarbital tests on cognitive hemisphere functions. The SPET technique may help to explain atypical speech and memory responses caused by unusual intracranial vascularization.
在10例癫痫患者完成异戊巴比妥言语记忆测试后，将锝（99mTc）六甲基丙烯胺肟（HM-PAO）注入颈内动脉。将单光子发射计算机断层扫描（SPET）显示的脑灌注情况与脑血管造影结果进行比较，脑血管造影显示7例患者颅内血管单侧充盈。SPET显示这7例患者中有4例半球间存在交叉血流。在血管造影显示双侧造影剂充盈的3例患者中，SPET仅显示2例存在交叉血流。得出的结论是，99mTc-HM-PAO SPET检查为正确解释异戊巴比妥对认知半球功能的测试提供了有价值的信息。SPET技术可能有助于解释由异常颅内血管形成引起的非典型言语和记忆反应。
