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儿童犬弓首蛔虫感染的患病率及相关危险因素

Prevalence and risk factors associated with Toxocara canis infection in children.

作者信息

Romero Núñez Camilo, Mendoza Martínez Germán David, Yañez Arteaga Selene, Ponce Macotela Martha, Bustamante Montes Patricia, Ramírez Durán Ninfa

机构信息

Centro Universitario Amecameca, Universidad Autónoma del Estado de México, 56900 Amecameca, MEX, Mexico.

出版信息

ScientificWorldJournal. 2013 Jun 9;2013:572089. doi: 10.1155/2013/572089. Print 2013.

Abstract

The objective of this study was to determine seroprevalence and identify risk factors associated with Toxocara canis infection. A clinical and epidemiological questionnaire and body mass index were used to assess the risk factors associated with human toxocariasis in 108 children with an age range of 2-16 years. Antibodies against Toxocara canis were detected using an ELISA test kit. Chi-square analysis and odds ratio (OR) were used to identify risk factors associated with Toxocara canis seropositivity. The prevalence of antibodies against Toxocara canis was greater (P = 0.02) in males than females (28.84% and 16.07%, resp.). Chi-square analysis and odds ratio revealed just one variable with P < 0.05, and OR > 1.0 was associated with seropositivity: the possession of dogs under one year old (OR = 1.78). Although not significant, the OR values suggest that other factors may be epidemiologically important for Toxocara presence such as not washing hands before meals, malnutrition, obesity, and use of public parks. Children in the age group >12 and <16 years old had higher seroprevalence to Toxocara canis (17.59%) than the >2 and <11 years old age group (4.62%). Toxocariosis infection needs to be prevented by pet deworming and hygienic measures after contact with dogs.

摘要

本研究的目的是确定犬弓首蛔虫感染的血清阳性率,并识别与之相关的风险因素。采用临床和流行病学调查问卷以及体重指数来评估108名年龄在2至16岁儿童中与人类弓首蛔虫病相关的风险因素。使用酶联免疫吸附测定(ELISA)试剂盒检测抗犬弓首蛔虫抗体。采用卡方分析和比值比(OR)来识别与犬弓首蛔虫血清阳性相关的风险因素。男性抗犬弓首蛔虫抗体的患病率高于女性(分别为28.84%和16.07%,P = 0.02)。卡方分析和比值比显示,只有一个变量P < 0.05且OR > 1.0与血清阳性相关:拥有一岁以下的犬只(OR = 1.78)。尽管不显著,但OR值表明其他因素在流行病学上可能对犬弓首蛔虫的存在很重要,如饭前不洗手、营养不良、肥胖以及使用公园。12至16岁年龄组的儿童对犬弓首蛔虫的血清阳性率(17.59%)高于2至11岁年龄组(4.62%)。需要通过宠物驱虫以及接触犬只后的卫生措施来预防弓首蛔虫病感染。

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