IEEE Trans Biomed Circuits Syst. 2011 Dec;5(6):511-22. doi: 10.1109/TBCAS.2011.2177661.
A low-power, wireless, and implantable microstimulator system on chip with smart powering management, immediate neural signal acquisition, and wireless rechargeable system is proposed. A system controller with parity checking handles the adjustable stimulus parameters for the stimulated objective. In the current paper, the rat's intra-cardiac electrogram is employed as the stimulated model in the animal study, and it is sensed by a low-voltage and low-power monitoring analog front end. The power management unit, which includes a rectifier, battery charging and detection, and a regulator, is used for the power control of the internal circuits. The stimulation data and required clock are extracted by a phase-locked-loop-based phase shift keying demodulator from an inductive AC signal. The full chip, which consumes 48 μW only, is fabricated in a TSMC 0.35 μm 2P4M standard CMOS process to perform the monitoring and pacing functions with inductively powered communication in the in vivo study.
提出了一种具有智能电源管理、即时神经信号采集和无线充电系统的低功耗、无线、可植入微刺激器系统芯片。系统控制器具有奇偶校验功能，可处理刺激目标的可调刺激参数。在本文中，大鼠的心脏内电图被用作动物研究中的刺激模型，由低压低功耗监测模拟前端进行感应。电源管理单元包括整流器、电池充电和检测以及稳压器，用于内部电路的电源控制。基于锁相环的相移键控解调器从感应交流信号中提取刺激数据和所需时钟。该全芯片仅消耗 48 μW，采用 TSMC 0.35 μm 2P4M 标准 CMOS 工艺制造，可在体内研究中进行监测和起搏功能，并进行感应供电通信。
