IEEE Trans Biomed Circuits Syst. 2010 Dec;4(6):462-8. doi: 10.1109/TBCAS.2010.2079932.
This paper presents a dual-mode capsule gastrointestinal endoscope device. An endoscope combined with a narrowband image (NBI), has been shown to be a superior diagnostic tool for early stage tissue neoplasms detection. Nevertheless, a wireless capsule endoscope with the narrowband imaging technology has not been presented in the market up to now. The narrowband image acquisition and power dissipation reduction are the main challenges of NBI capsule endoscope. In this paper, we present the first narrowband imaging capsule endoscope that can assist clinical doctors to effectively diagnose early gastrointestinal cancers, profited from our dedicated dual-mode complementary metal-oxide semiconductor (CMOS) sensor. The dedicated dual-mode CMOS sensor can offer white-light and narrowband images. Implementation results show that the proposed 512 × 512 CMOS sensor consumes only 2 mA at a 3-V power supply. The average current of the NBI capsule with an 8-Mb/s RF transmitter is nearly 7 ~ 8 mA that can continuously work for 6 ~ 8 h with two 1.5-V 80-mAh button batteries while the frame rate is 2 fps. Experimental results on backside mucosa of a human tongue and pig's small intestine showed that the wireless NBI capsule endoscope can significantly improve the image quality, compared with a commercial-of-the-shelf capsule endoscope for gastrointestinal tract diagnosis.
本文提出了一种双模式胶囊式胃肠道内窥镜设备。已经证明，内窥镜结合窄带成像（NBI）是早期组织肿瘤检测的优越诊断工具。然而，到目前为止，市场上还没有带有窄带成像技术的无线胶囊内窥镜。窄带图像采集和功耗降低是 NBI 胶囊内窥镜的主要挑战。在本文中，我们提出了第一个能够协助临床医生有效诊断早期胃肠道癌症的窄带成像胶囊内窥镜，这得益于我们专用的双模互补金属氧化物半导体（CMOS）传感器。专用双模 CMOS 传感器可以提供白光和窄带图像。实现结果表明，所提出的 512×512 CMOS 传感器在 3V 电源下仅消耗 2mA 的电流。具有 8-Mb/s RF 发射器的 NBI 胶囊的平均电流接近 7-8mA，使用两个 1.5V 80mAh 的纽扣电池可以连续工作 6-8 小时，帧率为 2fps。在人体舌背侧黏膜和猪小肠上的实验结果表明，与用于胃肠道诊断的商业现成胶囊内窥镜相比，无线 NBI 胶囊内窥镜可以显著提高图像质量。
