Chongqing Key Laboratory of Colleges and Universities on Micro-Nano Systems Technology and Smart Transducing, Chongqing Engineering Laboratory for Detection, Institute of Applied Micro-Nano Science and Technology-IAMNST, Control and Integrated System, National Research Base of Intelligent Manufacturing Service, Chongqing Technology and Business University, Nan'an District,Chongqing 400067, China.
CMEMS-UMinho, Department of Industrial Electronics, University of Minho, 4800-058 Guimaraes, Portugal.
Sensors (Basel). 2019 Mar 1;19(5):1057. doi: 10.3390/s19051057.
Minimally invasive medical devices can greatly benefit from Narrow Band Imaging (NBI) diagnostic capabilities, as different wavelengths allow penetration of distinct layers of the gastrointestinal tract mucosa, improving diagnostic accuracy and targeting different pathologies. An important performance parameter is the light intensity at a given power consumption of the medical device. A method to increase the illumination intensity in the NBI diagnostic technique was developed and applied to minimally invasive medical devices (e.g., endoscopic capsules), without increasing the size and power consumption of such instruments. Endoscopic capsules are generally equipped with light-emitting diodes (LEDs) operating in the RGB (red, green, and blue) visible light spectrum. A polydimethylsiloxane (PDMS) µ-lens was designed for a maximum light intensity at the target area of interest when placed on top of the LEDs. The PDMS µ-lens was fabricated using a low-cost hanging droplet method. Experiments reveal an increased illumination intensity by a factor of 1.21 for both the blue and green LEDs and 1.18 for the red LED. These promising results can increase the resolution of NBI in endoscopic capsules, which can contribute to early gastric lesions diagnosis.
微创医疗器械可以极大地受益于窄带成像（NBI）诊断功能，因为不同的波长允许穿透胃肠道黏膜的不同层，从而提高诊断准确性并针对不同的病理。一个重要的性能参数是给定医疗设备功耗下的光强度。本研究开发了一种在不增加仪器尺寸和功耗的情况下，提高 NBI 诊断技术中照明强度的方法，并将其应用于微创医疗器械（例如，内窥镜胶囊）。内窥镜胶囊通常配备在可见光谱的 RGB（红、绿、蓝）中工作的发光二极管（LED）。设计了一种用于在 LED 顶部放置时将光强最大化到目标感兴趣区域的聚二甲基硅氧烷（PDMS）微透镜。PDMS 微透镜使用低成本的悬挂液滴法制造。实验表明，蓝色和绿色 LED 的光强度增加了 1.21 倍，红色 LED 的光强度增加了 1.18 倍。这些有前景的结果可以提高内窥镜胶囊中 NBI 的分辨率，有助于早期胃损伤的诊断。
