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首例菲律宾旅行返回韩国旅行者感染 PVL 阳性 ST30 社区相关耐甲氧西林金黄色葡萄球菌克隆导致的皮肤感染病例。

First imported case of skin infection caused by PVL-positive ST30 community-associated methicillin-resistant Staphylococcus aureus clone in a returning Korean traveler from the Philippines.

机构信息

Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

J Korean Med Sci. 2013 Jul;28(7):1100-2. doi: 10.3346/jkms.2013.28.7.1100. Epub 2013 Jul 3.

DOI:10.3346/jkms.2013.28.7.1100
PMID:23853497
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3708085/
Abstract

Although pandemic community-associated (CA-) methicillin-resistant Staphylococcus aureus (MRSA) ST30 clone has successfully spread into many Asian countries, there has been no case in Korea. We report the first imported case of infection caused by this clone in a Korean traveler returning from the Philippines. A previously healthy 30-yr-old Korean woman developed a buttock carbuncle while traveling in the Philippines. After coming back to Korea, oral cephalosporin was given by a primary physician without any improvement. Abscess was drained and MRSA strain isolated from her carbuncle was molecularly characterized and it was confirmed as ST30-MRSA-IV. She was successfully treated with vancomycin and surgery. Frequent international travel and migration have increased the risk of international spread of CA-MRSA clones. The efforts to understand the changing epidemiology of CA-MRSA should be continued, and we should raise suspicion of CA-MRSA infection in travelers with skin infections returning from CA-MRSA-endemic countries.

摘要

虽然流行社区相关性(CA-)耐甲氧西林金黄色葡萄球菌(MRSA)ST30 克隆已成功传播到许多亚洲国家,但韩国尚未出现病例。我们报告了首例从菲律宾旅行返回的韩国旅行者感染该克隆的输入性病例。一名 30 岁的既往健康韩国女性在菲律宾旅行时臀部出现痈。回到韩国后,初级医生给予口服头孢菌素治疗,但没有任何改善。脓肿切开引流,从她的痈中分离出的 MRSA 菌株进行了分子特征分析,证实为 ST30-MRSA-IV。她成功地接受了万古霉素和手术治疗。频繁的国际旅行和移民增加了 CA-MRSA 克隆的国际传播风险。应继续努力了解 CA-MRSA 的不断变化的流行病学,对于从 CA-MRSA 流行国家返回的旅行者中出现皮肤感染,应怀疑 CA-MRSA 感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caae/3708085/64b39cbf57c1/jkms-28-1100-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caae/3708085/64b39cbf57c1/jkms-28-1100-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caae/3708085/64b39cbf57c1/jkms-28-1100-g001.jpg

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