2型糖尿病患者肥胖与血清25-羟维生素D3水平的关系
Relation of obesity with serum 25 hydroxy vitamin D3 levels in type 2 diabetic patients.
作者信息
Cimbek Ahmet, Gürsoy Gül, Kirnap Nazli Gülsoy, Acar Yaşar, Kiliç Zuhal, Güngör Fatih, Ozaşik Işil
机构信息
Department of Internal Medicine, Ankara Education and Research Hospital, Ankara, Turkey.
出版信息
J Res Med Sci. 2012 Dec;17(12):1119-23.
BACKGROUND
Hypovitaminosis D is associated with diabetes mellitus (DM). Aim of our study was to determine the relation of obesity with vitamin D levels in type 2 diabetic patients.
MATERIALS AND METHODS
We examined 101 type 2 diabetic patients and made a correlation analysis in all parameters. Then we classified our diabetics according to their body-mass indices and compared their 25 hdroxy vitamin D3 levels.
RESULTS
We found negative correlation between 25O HD and body mass index (BMI) (P: <0.001, r: -0.23). When we classified our diabetics according to their body mass indices as normal, overweight and obese, and compared their 25 hydroxy vitamin D3 levels, we determined that in every BMI group 25 hydroxy vitamin D levels were not found to be significantly different.
CONCLUSION
These results suggest that at least in a Turkish population with type 2 DM vitamin D levels are low and correlate with BMI, but when vitamin D levels are so low, as obesity worsens vitamin D levels does not lessen.
背景
维生素D缺乏与糖尿病（DM）相关。我们研究的目的是确定2型糖尿病患者中肥胖与维生素D水平的关系。
材料与方法
我们检查了101例2型糖尿病患者，并对所有参数进行了相关性分析。然后我们根据糖尿病患者的体重指数进行分类，并比较他们的25羟维生素D3水平。
结果
我们发现25O HD与体重指数（BMI）之间存在负相关（P：<0.001，r：-0.23）。当我们根据糖尿病患者的体重指数将其分为正常、超重和肥胖，并比较他们的25羟维生素D3水平时，我们确定在每个BMI组中，25羟维生素D水平没有显著差异。
结论
这些结果表明，至少在土耳其2型糖尿病患者人群中，维生素D水平较低且与BMI相关，但当维生素D水平非常低时，随着肥胖程度加重，维生素D水平并未降低。
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