Department of Medicine (Cardiovascular Division), Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, USA.
J Magn Reson Imaging. 2014 Jan;39(1):179-88. doi: 10.1002/jmri.24098. Epub 2013 Jul 15.
To improve compressed sensing (CS) reconstruction of accelerated breath-hold (BH) radial cine magnetic resonance imaging (MRI) by exploiting auxiliary data acquired between different BHs.
Cardiac function is usually assessed using segmented cine acquisitions over multiple BHs to cover the entire left ventricle (LV). Subjects are given a resting period between adjacent BHs, when conventionally no data are acquired and subjects rest in the scanner. In this study the resting periods between BHs were used to acquire additional free-breathing (FB) data, which are subsequently used to generate a sparsity constraint for each cardiac phase. Images reconstructed using the proposed sparsity constraint were compared with conventional CS using a composite image generated by averaging different cardiac phases. The efficacy of the proposed reconstruction was compared using indices of LV function and blood-myocardium sharpness.
The proposed method provided accurate LV ejection fraction measurements for 33% and 20% sampled datasets compared with fully sampled reference images, and showed 14% and 11% higher blood-myocardium border sharpness scores compared to the conventional CS.
The FB data acquired during resting periods can be efficiently used to improve the image quality of the undersampled BH data without increasing the total scan time.
通过利用在不同屏气(BH)之间采集的辅助数据来提高加速 BH 径向电影磁共振成像(MRI)的压缩感知(CS)重建。
心脏功能通常使用多个 BH 上的分段电影采集进行评估,以覆盖整个左心室(LV)。在相邻 BH 之间,患者会有一个休息期,此时传统上不会采集数据,患者在扫描仪中休息。在这项研究中,BH 之间的休息期用于采集额外的自由呼吸(FB)数据,随后用于为每个心脏相位生成稀疏约束。使用由不同心脏相位平均生成的复合图像,比较使用所提出的稀疏约束重建的图像与传统 CS。使用 LV 功能和血液-心肌锐度指数比较所提出的重建方法的效果。
与完全采样参考图像相比,该方法为 33%和 20%采样数据集提供了准确的 LV 射血分数测量值,并且与传统 CS 相比,血液-心肌边界锐度评分分别高 14%和 11%。
在休息期采集的 FB 数据可有效地用于提高欠采样 BH 数据的图像质量,而不会增加总扫描时间。