Bumbacea R S, Ghiordanescu I
Department of Allergology, Universitary Emergency Elias Hospital, Bucharest, Romania.
Eur Ann Allergy Clin Immunol. 2013 May;45(3):109-10.
Type I hypersensitivity reactions have been described after solid organ transplantation despite T cell targeted immunosuppressive therapy. There are several reports of food allergy, asthma and eosinophilic colitis in pediatric transplant recipients under Tacrolimus immunosuppression, but not Cyclosporine A. We present the case of a 6 year old patient that developed de novo atopic dermatitis, eosinophilia and high levels of total IgE under systemic treatment with tacrolimus.
尽管采用了针对T细胞的免疫抑制疗法，但实体器官移植后仍有I型超敏反应的报道。有几篇报道称，接受他克莫司免疫抑制治疗而非环孢素A治疗的儿科移植受者出现了食物过敏、哮喘和嗜酸性粒细胞性结肠炎。我们报告了一例6岁患者的病例，该患者在接受他克莫司全身治疗后出现了新发特应性皮炎、嗜酸性粒细胞增多和总IgE水平升高。
