Department of Health Promotion and Health Education, National Taiwan Normal University, No. 162, He-Ping East Road, Section 1, Taipei 10610, Taiwan.
BMC Psychiatry. 2013 Jul 16;13:190. doi: 10.1186/1471-244X-13-190.
This study examined long-term improvement of quality of life amongst heroin users enrolled in methadone maintenance treatment (MMT).
The sample contained 553 heroin-dependent individuals from 4 hospitals in northern Taiwan who enrolled in MMT for an average of 184 days. Each patient signed a consent form and was assessed prospectively 3 times semi-annually. Quality of life was measured using the WHOQOL-BREF questionnaire, 26 items of which were scored by the participants. The WHOQOL-BREF consists of four domains: physical, psychological, social, and environmental. 285 and 155 participants completed 6-month and 12-month follow-ups respectively.
After controlling for demographic and clinical characteristics, there were statistically significant improvements in the psychological and environmental domains between baseline and 6 months. Significant improvements were found in psychological and social domains between baseline and 12 months.
It is concluded that methadone maintenance treatment improves heroin users' long-term quality of life in the psychological and social relationship domains.
本研究旨在探讨参加美沙酮维持治疗（MMT）的海洛因使用者的生活质量长期改善情况。
该样本包含了来自台湾北部 4 家医院的 553 名海洛因依赖者，他们参加 MMT 的平均时间为 184 天。每位患者均签署了同意书，并在 3 次半年度前瞻性评估中进行了评估。使用 WHOQOL-BREF 问卷测量生活质量，其中 26 个项目由参与者进行评分。WHOQOL-BREF 由四个领域组成：身体、心理、社会和环境。分别有 285 名和 155 名参与者完成了 6 个月和 12 个月的随访。
在控制人口统计学和临床特征后，基线和 6 个月之间心理和环境领域的生活质量有统计学意义的改善。在基线和 12 个月之间，心理和社会领域的生活质量也有显著改善。
美沙酮维持治疗可改善海洛因使用者在心理和社会关系领域的长期生活质量。
