Soydinc H E, Kan I, Dal T, Evsen M S, Sak M E, Ozler A, Turgut A, Yildiz I
Department of Gynecology and Obstetrics, Dicle University School of Medicine, Diyarbakir, Turkey.
Clin Ter. 2013 May-Jun;164(3):e199-202. doi: 10.7417/CT.2013.1568.
The aim of the present study was to investigate the association between maternal infections and preeclampsia.
Fifty-four pregnant women with preeclampsia (study group) and 54 healthy pregnant women (control group) were enrolled in this study. Chlamydia pneumoniae (CP), Mycoplasma hominis (MH), Helicobacter pylori (HP), Cytomegalovirus (CMV), Herpes simplex virus type 2 (HSV-2), and Toxoplasma gondii (TG) antibodies were analyzed in the maternal plasma of all of the participants.
There was no difference in the demographic data between groups. Maternal plasma seropositivity for CP IgM; MH IgA and IgG; HP IgM, IgA and IgG; TG, CMV and HSV-2 IgM and IgG were not significantly different between the preeclampsia and control groups. The seropositivity for CP IgG was significantly higher in women with preeclampsia versus the control women.
Our results suggested that preeclampsia is associated with CP IgG seropositivity.
本研究旨在调查孕产妇感染与先兆子痫之间的关联。
本研究纳入了54例先兆子痫孕妇（研究组）和54例健康孕妇（对照组）。分析了所有参与者母血中肺炎衣原体（CP）、人型支原体（MH）、幽门螺杆菌（HP）、巨细胞病毒（CMV）、2型单纯疱疹病毒（HSV-2）和弓形虫（TG）抗体。
两组间人口统计学数据无差异。先兆子痫组与对照组孕妇血浆中CP IgM、MH IgA和IgG、HP IgM、IgA和IgG、TG、CMV和HSV-2 IgM及IgG的血清阳性率无显著差异。先兆子痫女性CP IgG血清阳性率显著高于对照女性。
我们的结果表明，先兆子痫与CP IgG血清阳性有关。
