Abe Shinichi, Fukuda Masayuki, Yamane Shigeki, Saka Hideki, Katori Yukio, Rodríguez-Vázquez Jose Francisco, Murakami Gen
Department of Anatomy, Tokyo Dental College, Chiba, Japan. ; Oral Health Science Center hrc8, Tokyo Dental College, Chiba, Japan.
Anat Cell Biol. 2013 Jun;46(2):141-8. doi: 10.5115/acb.2013.46.2.141. Epub 2013 Jun 30.
We examined pharyngeal nerve courses in paraffin-embedded sagittal sections from 10 human fetuses, at 25-35 weeks of gestation, by using S100 protein immunohistochemical analysis. After diverging from the glossopharyngeal and vagus nerves at the level of the hyoid bone, the pharyngeal nerves entered the constrictor pharyngis medius muscle, then turned upward and ran superiorly and medially through the constrictor pharyngis superior muscle, to reach either the levator veli palatini muscle or the palatopharyngeus muscle. None of the nerves showed a tendency to run along the posterior surface of the pharyngeal muscles. Therefore, the pharyngeal nerve plexus in adults may become established by exposure of the fetal intramuscular nerves to the posterior aspect of the pharyngeal wall because of muscle degeneration and the subsequent rearrangement of the topographical relationship between the muscles that occurs after birth.
我们通过S100蛋白免疫组织化学分析，在10例妊娠25至35周的人类胎儿石蜡包埋矢状切片中检查了咽神经走行。咽神经在舌骨水平从舌咽神经和迷走神经分出后，进入咽中缩肌，然后向上转折，在咽上缩肌内向上内侧走行，到达腭帆提肌或腭咽肌。没有神经显示出沿咽肌后表面走行的倾向。因此，成人的咽神经丛可能是由于胎儿肌内神经在出生后因肌肉退化以及随后肌肉之间地形关系的重新排列而暴露于咽壁后侧而形成的。
