1 University of Vermont College of Medicine, Burlington, Vermont.
Ann Am Thorac Soc. 2013 Oct;10(5):S45-97. doi: 10.1513/AnnalsATS.201304-090AW.
A conference, "Stem Cells and Cell Therapies in Lung Biology and Lung Diseases," was held July 25 to 28, 2011 at the University of Vermont to review the current understanding of the role of stem and progenitor cells in lung repair after injury and to review the current status of cell therapy and ex vivo bioengineering approaches for lung diseases. These are rapidly expanding areas of study that provide further insight into and challenge traditional views of mechanisms of lung repair after injury and pathogenesis of several lung diseases. The goals of the conference were to summarize the current state of the field, to discuss and debate current controversies, and to identify future research directions and opportunities for basic and translational research in cell-based therapies for lung diseases. The goal of this article, which accompanies the formal conference report, is to provide a comprehensive review of the published literature in lung regenerative medicine from the last conference report through December 2012.
一场名为“肺部生物学和肺部疾病中的干细胞和细胞疗法”的会议于 2011 年 7 月 25 日至 28 日在佛蒙特大学举行，旨在回顾目前对于干细胞和祖细胞在损伤后肺部修复中的作用的理解，并回顾细胞疗法和体外生物工程方法在肺部疾病中的应用现状。这些领域是研究的快速扩展领域，为损伤后肺部修复和几种肺部疾病发病机制的传统观点提供了更深入的见解和挑战。会议的目标是总结该领域的现状，讨论和辩论当前的争议，并确定未来的研究方向和机会，以便开展基于细胞的肺部疾病治疗的基础和转化研究。本文是对正式会议报告的补充，旨在对 2011 年会议报告以来至 2012 年 12 月间肺部再生医学领域的已发表文献进行全面综述。
