Vermont Lung Center, University of Vermont College of Medicine, Burlington, Vermont 05405, USA.
Proc Am Thorac Soc. 2011 Jun;8(3):223-72. doi: 10.1513/pats.201012-071DW.
The University of Vermont College of Medicine and the Vermont Lung Center, with support of the National Heart, Lung, and Blood Institute (NHLBI), the Alpha-1 Foundation, the American Thoracic Society, the Emory Center for Respiratory Health,the Lymphangioleiomyomatosis (LAM) Treatment Alliance,and the Pulmonary Fibrosis Foundation, convened a workshop,‘‘Stem Cells and Cell Therapies in Lung Biology and Lung Diseases,’’ held July 26-29, 2009 at the University of Vermont,to review the current understanding of the role of stem and progenitor cells in lung repair after injury and to review the current status of cell therapy approaches for lung diseases. These are rapidly expanding areas of study that provide further insight into and challenge traditional views of the mechanisms of lung repair after injury and pathogenesis of several lung diseases. The goals of the conference were to summarize the current state of the field, discuss and debate current controversies, and identify future research directions and opportunities for both basic and translational research in cell-based therapies for lung diseases.
佛蒙特大学医学院和佛蒙特肺脏中心在国家心肺血液研究所(NHLBI)、α-1 基金会、美国胸科学会、埃默里呼吸健康中心、淋巴管平滑肌瘤病(LAM)治疗联盟和肺纤维化基金会的支持下,于 2009 年 7 月 26 日至 29 日在佛蒙特大学召开了一次题为“肺生物学和肺部疾病中的干细胞和细胞疗法”的研讨会,旨在回顾目前对干细胞和祖细胞在损伤后肺修复中的作用的理解,并审查目前用于肺部疾病的细胞治疗方法的现状。这些是快速发展的研究领域,为损伤后肺修复的机制和几种肺部疾病的发病机制提供了更深入的见解和挑战传统观点。会议的目标是总结该领域的现状,讨论和辩论当前的争议,并确定未来的研究方向和机会,包括肺部疾病的基于细胞的治疗的基础和转化研究。