Department of Dermatology, University of Copenhagen, Bispebjerg Hospital, 2400 Copenhagen, Denmark.
Contact Dermatitis. 2013 Aug;69(2):107-11. doi: 10.1111/cod.12039.
Several instruments for the assessment of the severity of hand eczema and health-related quality of life (HR-QoL) related to hand eczema have been developed.
The aim of the present study was to evaluate the correlation between frequently used methods.
Consecutive patients with current hand eczema from three different centres participated in the study. Severity of hand eczema was assessed with the Hand Eczema Severity Index (HECSI), the Physician Global Assessment (PGA), the Clinical Photo Guide, and the Dermatology Life Quality Index (DLQI).
One hundred and nineteen patients with hand eczema were included in the study. All six pairwise correlation coefficients between the tested methods were highly statistically significant. Correlation was highest between the HECSI and the PGA (r = 0.82), and weakest, although still statistically significant, between the DLQI and the other three severity scores (r between 0.30 and 0.45). Age and frequency of eruptions did not influence the correlations. With respect to sex, there was a tendency for correlation between methods to be higher for men than for women.
We found an overall positive correlation between the four severity assessments applied. As the weakest correlation was found between the DLQI and the other methods, it is suggested that measurement of HR-QoL should be included for assessment of the severity and consequences of hand eczema, but the finding also indicates that a disease-specific tool for evaluation of HR-QoL in hand eczema patients is needed.
已经开发出几种用于评估手部湿疹严重程度和与手部湿疹相关的健康相关生活质量（HR-QoL）的工具。
本研究旨在评估常用方法之间的相关性。
来自三个不同中心的当前手部湿疹的连续患者参与了这项研究。手部湿疹的严重程度使用手部湿疹严重程度指数（HECSI）、医生整体评估（PGA）、临床照片指南和皮肤病生活质量指数（DLQI）进行评估。
共有 119 名手部湿疹患者纳入本研究。所有六种测试方法之间的两两相关系数均具有统计学意义。HECSI 和 PGA 之间的相关性最高（r = 0.82），而 DLQI 与其他三种严重程度评分之间的相关性最弱（r 介于 0.30 和 0.45 之间），尽管仍然具有统计学意义。年龄和发作频率不影响相关性。就性别而言，方法之间的相关性对于男性高于女性。
我们发现应用的四种严重程度评估之间存在总体正相关。由于 DLQI 与其他方法之间的相关性最弱，因此建议在评估手部湿疹的严重程度和后果时应包括 HR-QoL 的测量，但这一发现也表明需要为手部湿疹患者评估 HR-QoL 开发一种特定疾病的工具。
