Maclean C, Flegg P J, Kilpatrick D C
Blood Transfusion Centre, Royal Infirmary, Edinburgh, Scotland, UK.
Clin Exp Immunol. 1990 Aug;81(2):263-6. doi: 10.1111/j.1365-2249.1990.tb03328.x.
Anti-cardiolipin antibodies of IgG class were found in 48% of intravenous drug users, 38% of homosexuals and 14% of heterosexuals (with no other risk factor) infected with HIV. Anti-cardiolipin antibodies were not increased in HIV-negative heterosexual partners of HIV-infected patients, but mildly elevated levels were detected in HIV-negative drug users, relative to healthy controls unselected for HIV status. Among HIV infected drug users, anti-cardiolipin antibodies were not associated with thrombocytopenia, Pneumocystis carinii pneumonia, disease progression or clinical stage. Anti-cardiolipin antibodies appear to be another non-specific marker of HIV infection which may be particularly common in male intravenous drug users infected with the virus.
在感染HIV的静脉吸毒者中，48%检测出IgG类抗心磷脂抗体；在感染HIV的同性恋者中，这一比例为38%；而在感染HIV的异性恋者（无其他风险因素）中，该比例为14%。HIV感染患者的HIV阴性异性伴侣中，抗心磷脂抗体并未增加，但相对于未根据HIV感染状况挑选的健康对照，HIV阴性吸毒者的抗心磷脂抗体水平有轻度升高。在感染HIV的吸毒者中，抗心磷脂抗体与血小板减少症、卡氏肺孢子虫肺炎、疾病进展或临床分期无关。抗心磷脂抗体似乎是HIV感染的另一种非特异性标志物，在感染该病毒的男性静脉吸毒者中可能尤为常见。
