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妊娠相关心肌梗死:病例报告及文献综述

Pregnancy-associated myocardial infarction : case report and review of the literature.

作者信息

Bezgin T, Geçmen Ç, Erden I, Esen A M

机构信息

Cardiology Clinic, Kartal Koşuyolu Heart&Research Hospital, Denizer Cad. Cevizli, 34846, Kartal-İstanbul, Turkey,

出版信息

Herz. 2014 Jun;39(4):530-3. doi: 10.1007/s00059-013-3856-5. Epub 2013 Jul 21.

Abstract

Acute myocardial infarction (AMI) is a rare, but possibly catastrophic event during pregnancy, delivery, or puerperium, leading to a high mortality rate. It has different pathogenic mechanisms, such as atherosclerosis, vasospasm, thrombosis, and coronary dissection. Although MI has been reported in pregnant women at all stages of pregnancy and postpartum, it occurs more commonly in the third trimester. Pregnancy-associated MI most commonly involves the anterior wall. Pregnancy itself is an independent risk factor for MI, conferring a fourfold higher risk than that of nonpregnant women matched for age. We report the case of a 27-year-old primigravida at 30 weeks' gestation presenting with anterior MI, secondary to severe stenosis of the left anterior descending coronary artery, treated with emergency percutaneous coronary intervention.

摘要

急性心肌梗死(AMI)在妊娠、分娩或产褥期是一种罕见但可能具有灾难性的事件,会导致高死亡率。它有不同的致病机制,如动脉粥样硬化、血管痉挛、血栓形成和冠状动脉夹层。虽然在妊娠各阶段及产后的孕妇中均有心肌梗死的报道,但更常见于孕晚期。妊娠相关心肌梗死最常累及前壁。妊娠本身是心肌梗死的一个独立危险因素,其风险比年龄匹配的非孕妇高四倍。我们报告一例27岁初产妇,孕30周时因左前降支冠状动脉严重狭窄继发前壁心肌梗死,接受了急诊经皮冠状动脉介入治疗。

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