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下丘脑背内侧核在自主神经和神经内分泌稳态中的作用。

The dorsomedial hypothalamic nucleus in autonomic and neuroendocrine homeostasis.

作者信息

Bernardis L L

出版信息

Can J Neurol Sci. 1975 Feb;2(1):45-60. doi: 10.1017/s0317167100019971.

DOI:10.1017/s0317167100019971
PMID:238734
Abstract

Median eminence and ventromedial hypothalamus have in the past been the principal foci of research in neuroendocrine and neurovisceral control mechanisms. The present report provides an overview of work involving the dorsomedial hypothalamic nucleus (DMV). This structure is located dorsal to the ventromedial hypothalamic nucleus (VMN) to the plane of the dorsal premammillary nucleus. Fibers from the DMN pass with the periventricular system and the dorsal longitudinal fasciculus of Schütz and have been traced to the midbrain tegmentum and reticular formation. Intrahypothalamic connections involve intensive networks between DMN, lateral hypothalamic nucleus (LHN) and VMN. Regarding neurotransmitters, recent studies indicate that the DMN receives noradrenergic innervation along two pathways, a dorsal and a ventral one. Monoamine-containing systems approach the DMN From the lateral hypothalamus and the bulk of these fibers are carried in the medium forebrain bundle from their cells of origin in the brain stem. Studies of the vascular supply indicate that both VMN and DMN receive their blood supply from the internal carotid artery...

摘要

过去,正中隆起和下丘脑腹内侧核一直是神经内分泌和神经内脏控制机制研究的主要焦点。本报告概述了涉及下丘脑背内侧核(DMV)的研究工作。该结构位于下丘脑腹内侧核(VMN)背侧至乳头体前背核平面。来自DMN的纤维与脑室周系统和舒茨背侧纵束同行,并已追踪至中脑被盖和网状结构。下丘脑内连接涉及DMN、下丘脑外侧核(LHN)和VMN之间的密集网络。关于神经递质,最近的研究表明,DMN沿两条途径接受去甲肾上腺素能神经支配,一条背侧途径和一条腹侧途径。含单胺的系统从下丘脑外侧接近DMN,这些纤维大部分通过中脑前脑束从脑干的起源细胞携带而来。血管供应研究表明,VMN和DMN均接受来自颈内动脉的血液供应……

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The dorsomedial hypothalamic nucleus in autonomic and neuroendocrine homeostasis.下丘脑背内侧核在自主神经和神经内分泌稳态中的作用。
Can J Neurol Sci. 1975 Feb;2(1):45-60. doi: 10.1017/s0317167100019971.
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Failure to demonstrate disruption of ultradian growth hormone rhythm and insulin secretion by dorsomedial hypothalamic nucleus lesions that cause reduced body weight, linear growth and food intake.
未能通过导致体重、线性生长和食物摄入量减少的下丘脑背内侧核损伤来证明超日生长激素节律和胰岛素分泌的破坏。
Exp Brain Res. 1987;66(3):572-6. doi: 10.1007/BF00270690.