十二指肠溃疡和胃溃疡症状的发病年龄。
Age of onset of symptoms in duodenal and gastric ulcer.
作者信息
Kang J Y
机构信息
Department of Medicine, National University Hospital, Singapore.
出版信息
Gut. 1990 Aug;31(8):854-7. doi: 10.1136/gut.31.8.854.
The influence of the age of onset of symptoms on various clinical features of peptic ulcer was studied in a personal series of 492 patients (duodenal ulcer 363, gastric ulcer 98, combined gastric and duodenal ulcer 31). Duodenal ulcer patients whose age of onset of symptoms was within the first three decades (n = 166) were more likely to be men (77%) and to have a positive family history of dyspepsia (45%) and a history of haemorrhage (46%) when compared with late onset patients (n = 197, men 57%, positive family history 23%, history of haemorrhage 36%). Early onset duodenal ulcer patients also secreted more gastric acid than late onset patients. In contrast, while early onset gastric ulcer patients were more likely to be men, when compared to late onset patients, the two groups were similar in their family history of dyspepsia, their history of haemorrhage, and their gastric acid output. The age of onset of Malay duodenal ulcer patients (mean (SD) 43.6 (16.0] was higher than those for Chinese patients (33.7 (16.1].
在一项针对492例患者（十二指肠溃疡363例、胃溃疡98例、胃和十二指肠复合溃疡31例）的个人研究系列中，研究了症状发作年龄对消化性溃疡各种临床特征的影响。与症状发作较晚的患者（n = 197，男性占57%，消化不良家族史阳性占23%，出血史占36%）相比，症状发作年龄在头三十年以内的十二指肠溃疡患者（n = 166）更可能为男性（77%），有消化不良家族史阳性（45%）和出血史（46%）。症状发作早的十二指肠溃疡患者分泌的胃酸也比症状发作晚的患者多。相比之下，虽然症状发作早的胃溃疡患者更可能为男性，但与症状发作晚的患者相比，两组在消化不良家族史、出血史和胃酸分泌量方面相似。马来族十二指肠溃疡患者的症状发作年龄（均值（标准差）43.6（16.0））高于华裔患者（33.7（16.1））。
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