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儿童上呼吸道消化道局灶性黏蛋白沉积症

Focal mucinosis of the upper aerodigestive tract in children.

作者信息

Gnepp D R, Vogler C, Sotelo-Avila C, Kielmovitch I H

机构信息

Department of Pathology, St Louis University School of Medicine, MO.

出版信息

Hum Pathol. 1990 Aug;21(8):856-8. doi: 10.1016/0046-8177(90)90056-b.

Abstract

Cutaneous mucinosis is an uncommon lesion characterized by mucin accumulation in the dermis. Rarely, mucinosis may arise in the oral cavity; reported cases have been observed in patients older than 16 years. We identified two children younger than 5 years of age with focal mucinosis of the upper aerodigestive tract. A 3-year-old boy had been intubated at age 2 months, suffered from recurrent respiratory infections, and developed mucinosis of the larynx, a previously unreported site for this unusual lesion. The second patient, a 4-year-old girl with a cleft palate, developed palatine mucinosis.

摘要

皮肤粘蛋白沉积症是一种罕见的病变,其特征是真皮内粘蛋白积聚。粘蛋白沉积症很少发生在口腔;已报道的病例见于16岁以上的患者。我们发现了两名5岁以下患有上呼吸道消化道局灶性粘蛋白沉积症的儿童。一名3岁男孩在2个月大时曾接受插管治疗,患有反复呼吸道感染,并患上了喉粘蛋白沉积症,这是这种罕见病变以前未报道过的发病部位。第二名患者是一名患有腭裂的4岁女孩,患上了腭粘蛋白沉积症。

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