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腭部口腔局灶性黏蛋白沉积症:一种罕见的疾病实体。

Oral focal mucinosis of the palate: a rare disease entity.

作者信息

Cameron Alice, Webster James Edward Noctun, Wicks Catherine Elizabeth, Colbert Serryth Dominic

机构信息

Department of Oral and Maxillofacial Surgery, Royal United Hospital Bath NHS Trust, Bath, UK

Department of Oral and Maxillofacial Surgery, Royal United Hospital Bath NHS Trust, Bath, UK.

出版信息

BMJ Case Rep. 2020 Mar 10;13(3):e230233. doi: 10.1136/bcr-2019-230233.

Abstract

Oral focal mucinosis (OFM) is an extremely rare, benign oral soft tissue condition; less than 10 documented cases have been reported in the literature in patients under 18 years old. OFM has an unknown aetiology and predominantly presents in the fourth and fifth decades. The pathogenesis of OFM may be due to fibroblast overproduction of hyaluronic acid. Clinically, it remains almost impossible to diagnose definitively, due to its lack of pathognomonic features, therefore such lesions may have multiple differential diagnoses and histological analysis is essential to confirm OFM. We present an unusual presentation of OFM in a 14-year-old female patient. Following excision, focal myxoid degeneration of the connective tissue was apparent. This case highlights this rare condition for consideration in differential diagnosis of clinically similar lesions.

摘要

口腔局灶性黏液瘤(OFM)是一种极其罕见的良性口腔软组织疾病;文献报道18岁以下患者中记录在案的病例不足10例。OFM病因不明,主要出现在第四和第五个十年。OFM的发病机制可能是由于成纤维细胞过度产生透明质酸。临床上,由于缺乏特征性表现,几乎不可能明确诊断,因此此类病变可能有多种鉴别诊断,组织学分析对于确诊OFM至关重要。我们报告了一名14岁女性患者出现的不寻常的OFM表现。切除后,结缔组织出现局灶性黏液样变性。该病例突出了这种罕见疾病,以供临床类似病变的鉴别诊断时考虑。

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Oral focal mucinosis in an adolescent: A rare entity.青少年口腔局灶性黏液瘤病:一种罕见病症。
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