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突尼斯的皮肤结核。

Cutaneous tuberculosis in Tunisia.

机构信息

Service des maladies infectieuses, faculté de médecine de Tunis, université Tunis EL Manar, hôpital la Rabta, Tunis, Tunisia.

出版信息

Med Mal Infect. 2013 Sep;43(9):374-8. doi: 10.1016/j.medmal.2013.06.017. Epub 2013 Jul 19.

Abstract

INTRODUCTION

Tuberculosis is endemic in Tunisia. Pulmonary tuberculosis is the most common presentation in our country. Cutaneous presentations are rare (1-2% of cases). The diagnosis of cutaneous tuberculosis (CT) is difficult. Histological and clinical presentations are polymorphous, many differential diagnoses are available, and it is difficult to isolate Mycobacterium.

OBJECTIVE

We had for aim to study the epidemiological and clinical features of CT in Tunisia, and to compare presentations before and after 1990.

PATIENTS AND METHODS

We conducted a retrospective study between January 1991 and December 2011, in which we included all cases of CT observed at the Infectious Diseases and Dermatology Units of the Tunis la Rabta Hospital.

RESULTS

Hundred and thirty-seven patients were included, with a mean age of 43.8years; 72.3% were female patients. Hundred and fifty locations were observed, most of which on the head and neck. Scrofuloderma was the most frequent presentation, observed in 65% of cases. The diagnosis was confirmed by histology and/or microbiology in 75.8% of cases. The treatment was prescribed for a mean 11.3months, leading to full recovery in most cases.

CONCLUSION

CT is still reported in Tunisia. The diagnosis relies mainly on histology. Controlling this mutilating tuberculosis requires a global control of this disease, and especially lymph node location, given the high rate of scrofuloderma.

摘要

简介

结核病在突尼斯流行。肺结核是我国最常见的表现形式。皮肤表现较为少见(占病例的 1-2%)。皮肤结核(CT)的诊断具有一定难度。其组织学和临床表现呈多态性,存在许多鉴别诊断,且难以分离分枝杆菌。

目的

我们旨在研究突尼斯 CT 的流行病学和临床特征,并比较 1990 年前和 1990 年后的表现。

患者和方法

我们进行了一项回顾性研究,时间为 1991 年 1 月至 2011 年 12 月,纳入了突尼斯拉巴特医院传染病和皮肤科观察到的所有 CT 病例。

结果

共纳入 137 例患者,平均年龄为 43.8 岁;72.3%为女性患者。观察到 150 个病变部位,主要位于头颈部。瘰疬是最常见的表现,占 65%的病例。诊断在 75.8%的病例中通过组织学和/或微生物学证实。治疗的平均疗程为 11.3 个月,大多数患者完全康复。

结论

CT 在突尼斯仍有报告。诊断主要依赖于组织学。控制这种破坏性的结核病需要对该病进行全面控制,特别是淋巴结部位,因为瘰疬的发病率很高。

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