Ruiz Serrato A, Marín García D, Guerrero León M A, Vallejo Herrera M J, Villar Jiménez J, Cárdenas Lafuente F, García Ordóñez M A
Unidad de Gestión Clínica de Medicina Interna, Hospital de Antequera, Málaga, España.
Arch Soc Esp Oftalmol. 2013 Aug;88(8):323-6. doi: 10.1016/j.oftal.2011.09.024. Epub 2012 Aug 28.
An 18 year-old-woman presented with abdominal pain, diarrhea, and ptosis in her left eye. Nuclear magnetic resonance imaging (NMRI) and the study of cerebrospinal fluid detected no abnormalities. Colonoscopy revealed a Crohn's disease (CD) confirmed by histological examination of biopsies. Ocular symptoms improved after appropriate treatment of the underlying CD.
Inflammatory bowel disease (IBD) is associated with a wide variety of extra-intestinal manifestations, in fact it may be considered a systemic disorder with predominantly gastrointestinal tract manifestations. Extra-intestinal manifestations of inflammatory bowel disease (IBD) occur in one third of patients. Ocular complications are infrequent, occurring in less than 10% of cases, but can be associated with significant morbidity, including blindness. Ocular symptoms may precede a diagnosis of IBD. We report the first case of palpebral ptosis associated with Crohn's disease.
一名18岁女性出现腹痛、腹泻及左眼上睑下垂。核磁共振成像（NMRI）及脑脊液检查未发现异常。结肠镜检查发现克罗恩病（CD），活检组织学检查得以证实。基础疾病CD经适当治疗后，眼部症状有所改善。
炎症性肠病（IBD）与多种肠外表现相关，实际上它可被视为一种主要累及胃肠道的全身性疾病。炎症性肠病（IBD）的肠外表现在三分之一的患者中出现。眼部并发症并不常见，发生率低于10%，但可能导致严重的发病情况，包括失明。眼部症状可能在IBD诊断之前出现。我们报告了首例与克罗恩病相关的睑下垂病例。
