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[睑下垂,克罗恩病一种罕见的眼部表现]

[Palpebral ptosis, a rare ocular manifestation of Crohn's disease].

作者信息

Ruiz Serrato A, Marín García D, Guerrero León M A, Vallejo Herrera M J, Villar Jiménez J, Cárdenas Lafuente F, García Ordóñez M A

机构信息

Unidad de Gestión Clínica de Medicina Interna, Hospital de Antequera, Málaga, España.

出版信息

Arch Soc Esp Oftalmol. 2013 Aug;88(8):323-6. doi: 10.1016/j.oftal.2011.09.024. Epub 2012 Aug 28.

Abstract

CLINICAL CASE

An 18 year-old-woman presented with abdominal pain, diarrhea, and ptosis in her left eye. Nuclear magnetic resonance imaging (NMRI) and the study of cerebrospinal fluid detected no abnormalities. Colonoscopy revealed a Crohn's disease (CD) confirmed by histological examination of biopsies. Ocular symptoms improved after appropriate treatment of the underlying CD.

DISCUSSION

Inflammatory bowel disease (IBD) is associated with a wide variety of extra-intestinal manifestations, in fact it may be considered a systemic disorder with predominantly gastrointestinal tract manifestations. Extra-intestinal manifestations of inflammatory bowel disease (IBD) occur in one third of patients. Ocular complications are infrequent, occurring in less than 10% of cases, but can be associated with significant morbidity, including blindness. Ocular symptoms may precede a diagnosis of IBD. We report the first case of palpebral ptosis associated with Crohn's disease.

摘要

临床病例

一名18岁女性出现腹痛、腹泻及左眼上睑下垂。核磁共振成像(NMRI)及脑脊液检查未发现异常。结肠镜检查发现克罗恩病(CD),活检组织学检查得以证实。基础疾病CD经适当治疗后,眼部症状有所改善。

讨论

炎症性肠病(IBD)与多种肠外表现相关,实际上它可被视为一种主要累及胃肠道的全身性疾病。炎症性肠病(IBD)的肠外表现在三分之一的患者中出现。眼部并发症并不常见,发生率低于10%,但可能导致严重的发病情况,包括失明。眼部症状可能在IBD诊断之前出现。我们报告了首例与克罗恩病相关的睑下垂病例。

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