Institut de biologie intégrative et des systèmes, Pavillon Charles-Eugène-Marchand, Université Laval, 1030 avenue de la Médecine, Quebec City, QC, Canada G1V 0A6; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (Hôpital Laval), 2725 Chemin Sainte-Foy, Quebec City, QC, Canada G1V 4G5.
Faculté de Médecine Vétérinaire, Université de Montréal, 3200 rue Sicotte, St-Hyacinthe, QC, Canada J2S 7C6.
Vet Microbiol. 2014 Feb 21;169(1-2):1-7. doi: 10.1016/j.vetmic.2013.06.025. Epub 2013 Jul 9.
The bacterium Aeromonas salmonicida subsp. salmonicida is the causative agent of furunculosis, a systemic disease of fish in the salmonid family. Furunculosis is a ubiquitous disease that affects aquaculture operations worldwide and is characterized by high mortality and morbidity. A better understanding of the bacterium is required to find a cure. Thereby, this review centers on A. salmonicida subsp. salmonicida, its major virulence factors, and its genome. The classification and characteristics of A. salmonicida subsp. salmonicida, the virulence factors, such as the A-layer, extracellular molecules, and type three secretion system as well as the characteristics and plasticity of its genome are described.
嗜水气单胞菌亚种鲑鱼致疖病是鲑科鱼类全身性疖病的病原体。疖病是一种普遍存在的疾病，影响着全球水产养殖业务，其特点是高死亡率和发病率。为了找到治疗方法，需要更好地了解这种细菌。因此，本综述集中于嗜水气单胞菌亚种鲑鱼、其主要毒力因子及其基因组。描述了嗜水气单胞菌亚种鲑鱼的分类和特征、毒力因子，如 A 层、细胞外分子和 III 型分泌系统以及其基因组的特征和可塑性。
