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2
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本文引用的文献

1
The lactococcal phages Tuc2009 and TP901-1 incorporate two alternate forms of their tail fiber into their virions for infection specialization.乳球菌噬菌体 Tuc2009 和 TP901-1 将其尾部纤维的两种交替形式整合到其病毒粒子中，以实现感染的专业化。
J Biol Chem. 2013 Feb 22;288(8):5581-90. doi: 10.1074/jbc.M112.444901. Epub 2013 Jan 8.
2
Bacteriophage virion-associated peptidoglycan hydrolases: potential new enzybiotics.噬菌体病毒粒子相关肽聚糖水解酶：潜在的新型酶类抗生素。
Crit Rev Microbiol. 2013 Nov;39(4):427-34. doi: 10.3109/1040841X.2012.723675. Epub 2012 Sep 20.
3
Phage pierces the host cell membrane with the iron-loaded spike.噬菌体利用负载铁的刺突刺穿宿主细胞膜。
Structure. 2012 Feb 8;20(2):326-39. doi: 10.1016/j.str.2011.12.009.
4
Effects of bacteriophage traits on plaque formation.噬菌体特性对菌斑形成的影响。
BMC Microbiol. 2011 Aug 9;11:181. doi: 10.1186/1471-2180-11-181.
5
Peptidoglycan turnover and recycling in Gram-positive bacteria.革兰氏阳性菌中肽聚糖的周转和再循环。
Appl Microbiol Biotechnol. 2011 Oct;92(1):1-11. doi: 10.1007/s00253-011-3486-x. Epub 2011 Jul 28.
6
Lysis from without.外源性溶解
Bacteriophage. 2011 Jan;1(1):46-49. doi: 10.4161/bact.1.1.13980.
7
Lytic activity of the virion-associated peptidoglycan hydrolase HydH5 of Staphylococcus aureus bacteriophage vB_SauS-phiIPLA88.金黄色葡萄球菌噬菌体 vB_SauS-phiIPLA88 衣壳相关肽聚糖水解酶 HydH5 的溶菌活性。
BMC Microbiol. 2011 Jun 17;11:138. doi: 10.1186/1471-2180-11-138.
8
Morphogenesis of the T4 tail and tail fibers.T4 尾和尾丝的形态发生。
Virol J. 2010 Dec 3;7:355. doi: 10.1186/1743-422X-7-355.
9
Functional genomic analysis of two Staphylococcus aureus phages isolated from the dairy environment.从乳制品环境中分离的两个金黄色葡萄球菌噬菌体的功能基因组分析。
Appl Environ Microbiol. 2009 Dec;75(24):7663-73. doi: 10.1128/AEM.01864-09. Epub 2009 Oct 16.
10
Tape measure protein having MT3 motif facilitates phage entry into stationary phase cells of Mycobacterium tuberculosis.具有MT3基序的卷尺蛋白促进噬菌体进入结核分枝杆菌的稳定期细胞。
Comput Biol Chem. 2008 Oct;32(5):367-9. doi: 10.1016/j.compbiolchem.2008.03.016. Epub 2008 Apr 8.

金黄色葡萄球菌噬菌体 11 的肽聚糖水解酶在病毒粒子中起结构作用。

The peptidoglycan hydrolase of Staphylococcus aureus bacteriophage 11 plays a structural role in the viral particle.

机构信息

DairySafe Group, Department of Technology and Biotechnology of Dairy Products, Instituto de Productos Lácteos de Asturias (IPLA-CSIC), Villaviciosa, Asturias, Spain.

出版信息

Appl Environ Microbiol. 2013 Oct;79(19):6187-90. doi: 10.1128/AEM.01388-13. Epub 2013 Jul 26.

DOI:10.1128/AEM.01388-13
PMID:23892745
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3811384/
Abstract

The role of virion-associated peptidoglycan hydrolases (VAPGHs) in the phage infection cycle is not clear. gp49, the VAPGH from Staphylococcus aureus phage 11, is not essential for phage growth but stabilizes the viral particles. 11Δ49 phages showed a reduced burst size and delayed host lysis. Complementation of gp49 with HydH5 from bacteriophage vB_SauS-phiIPLA88 restored the wild-type phenotype.

摘要

病毒相关肽聚糖水解酶（VAPGHs）在噬菌体感染周期中的作用尚不清楚。来自金黄色葡萄球菌噬菌体 11 的 VAPGH gp49 对噬菌体生长并非必需，但可稳定病毒颗粒。11Δ49 噬菌体的爆发量减少，宿主裂解延迟。用噬菌体 vB_SauS-phiIPLA88 的 HydH5 对 gp49 进行互补，恢复了野生型表型。