输卵管异位妊娠中的氧化状态与血清脯氨酰二肽氨基肽酶活性
Oxidative status and serum prolidase activity in tubal ectopic pregnancy.
作者信息
Hilali Nese, Aksoy Nurten, Vural Mehmet, Camuzcuoglu Hakan, Taskin Abdullah
机构信息
Department of Obstetrics and Gynecology, University of Harran, Sanliurfa, Turkey.
出版信息
J Pak Med Assoc. 2013 Feb;63(2):169-72.
OBJECTIVE
To determine the oxidative status and serum prolidase activity in tubal ectopic pregnancy and to see if there was any association between them. MATHODS: The cross-sectional study was conducted during 2009 and 2010 at the Departments of Obstetrics and Gynaecology and Clinical Biochemistry under the Faculty of Medicine, Harran University, Turkey. It comprised 40 patients with tubal ectopic pregnancies and 42 women with healthy pregnancies. Serum prolidase activity was measured spectrophotometrically. Oxidative status was determined using total antioxidant capacity. SPSS 11.5 was used for statistical analysis.
RESULTS
Total antioxidant capacity levels were lower in the ectopic pregnancy group than the healthy group (p < 0.018), whereas total oxidant status, oxidative stress index and prolidase activity were higher (p < 0.05).
CONCLUSION
Ectopic pregnancy may be associated with increased serum prolidase activity and oxidative stress, and this association may help to provide a better understanding about the pathogenesis of ectopic pregnancy.
目的
测定输卵管异位妊娠患者的氧化状态及血清脯氨酰二肽氨基肽酶活性，并观察二者之间是否存在关联。方法：本横断面研究于2009年至2010年在土耳其哈兰大学医学院妇产科及临床生物化学科进行。研究对象包括40例输卵管异位妊娠患者和42例正常妊娠女性。采用分光光度法测定血清脯氨酰二肽氨基肽酶活性。通过总抗氧化能力测定氧化状态。使用SPSS 11.5进行统计分析。结果：异位妊娠组的总抗氧化能力水平低于正常妊娠组（p < 0.018），而总氧化状态、氧化应激指数及脯氨酰二肽氨基肽酶活性则较高（p < 0.05）。结论：异位妊娠可能与血清脯氨酰二肽氨基肽酶活性增加及氧化应激有关，这种关联可能有助于更好地理解异位妊娠的发病机制。
Zotero 插件