绿茶儿茶素诱导的吞噬作用可以被 catalase 和瞬时受体电位 melastatin 2（TRPM2）抑制剂阻断。
Green tea catechin induced phagocytosis can be blocked by catalase and an inhibitor of transient receptor potential melastatin 2 (TRPM2).
机构信息
NARO Institute of Vegetable and Tes Science, 2769 Kanaya-Shishidoi, Shimada, Shizuoka, 428-8501, Japan,
出版信息
Cytotechnology. 2014 Aug;66(4):561-6. doi: 10.1007/s10616-013-9618-7. Epub 2013 Jul 30.
Abstract
The major polyphenols in green tea, (-)-epigallocatechin and (-)-epigallocatechin gallate, have been shown to enhance the phagocytic activity of macrophage-like cells; however, the mechanism involved was not clarified. In this study, we have identified that the catechins induced phagocytosis can be blocked by catalase and an inhibitor of transient receptor potential melastatin 2.
摘要
绿茶中的主要多酚类物质（-）-表没食子儿茶素和（-）-表没食子儿茶素没食子酸酯已被证明能增强巨噬细胞样细胞的吞噬活性；然而，涉及的机制尚不清楚。在这项研究中，我们已经确定儿茶素诱导的吞噬作用可以被过氧化氢酶和瞬时受体电位 melastatin 2 的抑制剂阻断。
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