Budroni Mario, Cossu Antonio, Paliogiannis Panagiotis, Palmieri Giuseppe, Attene Federico, Cesaraccio Rosaria, Tanda Francesco
Ann Ital Chir. 2014 May-Jun;85(3):244-8.
The aim of this population-based study was to analyze and describe the epidemiological characteristics and trends of malignant pleural mesothelioma in the province of Sassari (Sardinia, Italy), in the period 1992-2010. Data were obtained from the local tumor registry which makes part of a wider registry web, coordinated today by the Italian Association for Tumor Registries. The overall number of malignant pleural mesothelioma cases registered was 70. The male-to-female ratio was 4:1 and the mean age 65.1 years for males and 63.4 years for females. The standardized incidence rates were 1.2/100,000 and 0.3/100,000 and the standardized mortality rates 0.6/100,000 and 0.2/100,000 for males and females respectively. A trend to increase in incidence in recent years was evidenced. This trend seems to follow the general national tendency and it depends on a large diffusion of asbestos usage in the past, delayed legislative interventions and probably a cleaning strategy of residual contamination fonts to intensify. The relative 5 years survival was low, suggesting the necessity to further intensify research and cure methods for the treatment of this extremely aggressive disease.
Asbestos exposure, Mesothelioma, Pleura, Sassari.
本基于人群的研究旨在分析和描述1992年至2010年期间意大利撒丁岛萨萨里省恶性胸膜间皮瘤的流行病学特征和趋势。数据来自当地肿瘤登记处，该登记处是一个更广泛的登记网络的一部分，目前由意大利肿瘤登记协会协调。登记的恶性胸膜间皮瘤病例总数为70例。男女比例为4:1，男性平均年龄为65.1岁，女性为63.4岁。男性和女性的标准化发病率分别为1.2/10万和0.3/10万，标准化死亡率分别为0.6/10万和0.2/10万。近年来发病率呈上升趋势。这一趋势似乎与全国总体趋势一致，这取决于过去石棉使用的广泛传播、立法干预的延迟以及可能需要加强对残留污染源头的清理策略。5年相对生存率较低，这表明有必要进一步加强对这种极具侵袭性疾病的研究和治疗方法。
石棉暴露、间皮瘤、胸膜、萨萨里
