1School of Physical Therapy and Athletic Training, Old Dominion University, Norfolk, VA; and 2School of Health Sciences and Human Performance, Ithaca College, Ithaca NY.
Med Sci Sports Exerc. 2014 Mar;46(3):546-56. doi: 10.1249/MSS.0b013e3182a6a93b.
Many studies have examined the temporal response of the peroneal muscles to sudden inversion perturbation in patients with a previous ankle sprain. The purpose of this systematic review with meta-analysis was to synthesize the evidence and determine whether peroneal reaction time (PRT) impairments are present after ankle sprain.
An electronic search was conducted using PubMed Central and EBSCOhost (1965-January 2013). Articles were included if they 1) examined the PRT to sudden inversion perturbation in patients with a history of ankle sprain using a mechanical tilt platform, 2) made comparisons with a control group or contralateral limb with no history of ankle sprain, and 3) provided data for the calculation of effect sizes (ES). In addition to examining the overall effect of sustaining an ankle sprain on PRT, the effects of study design and subject characteristics on PRT were evaluated. Bias-corrected Hedges g ES and 95% confidence intervals (CI) were calculated to make comparisons across studies.
A total of 23 studies met the inclusion criteria. The overall ES was 0.67 (95% CI = 0.37-0.95, P < 0.001), indicating that a previous ankle sprain, regardless of study design or subject characteristics, resulted in moderate-to-strong PRT deficits. Further analyses determined studies with patients classified as having chronic ankle instability demonstrated large magnitude PRT deficits in between groups (ES = 0.72, 95% CI = 0.29-1.14, P = 0.001) and side-to-side (ES = 1.24, 95% CI = 0.70-1.79, P < 0.001) comparisons, whereas patients with all other ankle sprain histories demonstrated weak PRT alterations in between groups (ES = -0.21, 95% CI = -1.01 to 0.59, P = 0.61) and side-to-side (ES = 0.21, 95% CI = -0.19 to 0.60, P = 0.31) comparisons.
Overall, this meta-analysis determined that individuals with a previous ankle sprain exhibit delayed PRT. Further analyses determined that these deficits are more evident in patients with chronic ankle instability when compared with the contralateral uninvolved limb or a healthy control group.
许多研究已经研究了腓骨肌对先前踝关节扭伤患者突然内翻扰动的时间反应。本系统评价的目的是综合证据并确定在踝关节扭伤后是否存在腓骨反应时间（PRT）损害。
使用 PubMed Central 和 EBSCOhost 进行电子搜索（1965 年-1 月 2013 年）。如果文章符合以下标准则纳入：1）使用机械倾斜平台检查有既往踝关节扭伤病史的患者的 PRT 对突然内翻干扰，2）与无踝关节扭伤病史的对照组或对侧肢体进行比较，3）提供计算效应大小（ES）的数据。除了检查踝关节扭伤对 PRT 的总体影响外，还评估了研究设计和受试者特征对 PRT 的影响。为了在研究之间进行比较，计算了校正后的 Hedges g ES 和 95%置信区间（CI）。
共有 23 项研究符合纳入标准。总体 ES 为 0.67（95%CI=0.37-0.95，P<0.001），表明先前的踝关节扭伤，无论研究设计或受试者特征如何，都会导致中度至重度的 PRT 缺陷。进一步的分析确定，将患有慢性踝关节不稳定的患者分类为患有慢性踝关节不稳定的患者在组间（ES=0.72，95%CI=0.29-1.14，P=0.001）和侧-侧（ES=1.24，95%CI=0.70-1.79，P<0.001）比较中存在较大的 PRT 缺陷，而具有所有其他踝关节扭伤病史的患者在组间（ES=-0.21，95%CI=-1.01 至 0.59，P=0.61）和侧-侧（ES=0.21，95%CI=-0.19 至 0.60，P=0.31）比较中仅表现出微弱的 PRT 变化。
总体而言，本荟萃分析确定先前有踝关节扭伤的个体表现出 PRT 延迟。进一步的分析确定，与对侧未受累肢体或健康对照组相比，慢性踝关节不稳定患者的这些缺陷更为明显。
