Public Health Department of Medical School, Zhejiang Provincial Key Laboratory of Pathological and Physiological Technology, Ningbo University, Ningbo, Zhejiang Province, People's Republic of China.
Int J Nanomedicine. 2013;8:2509-20. doi: 10.2147/IJN.S46919. Epub 2013 Jul 18.
Due to their chemical stability and nonallergic, nonirritant, and ultraviolet protective properties, titanium dioxide (TiO2) nanoparticles (NPs) have been widely used in industries such as electronics, optics, and material sciences, as well as architecture, medicine, and pharmacology. However, increasing concerns have been raised in regards to its ecotoxicity and toxicity on the aquatic environment as well as to humans. Although insights have been gained into the effects of TiO2 NPs on susceptible biological systems, there is still much ground to be covered, particularly in respect of our knowledge of the effects of the interaction of TiO2 NPs with other chemicals or physical factors. Studies suggest that interactions of TiO2 NPs with other chemicals or physical factors may result in an increase in toxicity or adverse effects. This review highlights recent progress in the study of the interactive effects of TiO2 NPs with other chemicals or physical factors.
由于其化学稳定性、无过敏性、无刺激性和紫外线防护性能，二氧化钛 (TiO2) 纳米粒子 (NPs) 已被广泛应用于电子、光学和材料科学等行业，以及建筑、医学和药理学领域。然而，人们越来越关注其对水生环境和人类的生态毒性和毒性。尽管人们对 TiO2 NPs 对敏感生物系统的影响有了一定的了解，但仍有许多方面需要研究，特别是在我们对 TiO2 NPs 与其他化学物质或物理因素相互作用的影响的了解方面。研究表明，TiO2 NPs 与其他化学物质或物理因素的相互作用可能会导致毒性或不良反应的增加。本综述重点介绍了 TiO2 NPs 与其他化学物质或物理因素相互作用的最新研究进展。
