通过电化学 E-DNA 支架传感器在未稀释血清中检测 IP-10 蛋白标志物。
Detection of IP-10 protein marker in undiluted blood serum via an electrochemical E-DNA scaffold sensor.
机构信息
Department of Chemistry, Metropolitan State University of Denver, Denver, CO 80217, USA.
出版信息
Analyst. 2013 Oct 7;138(19):5580-3. doi: 10.1039/c3an01079a.
Abstract
We describe an electrochemical analog of fluorescence polarization that supports the quantitative measurement of a specific protein, the chemokine IP-10, directly in undiluted blood serum. The sensor is label-free, wash-free, and electronic, suggesting it could support point-of-care detection of diagnostic proteins in largely unprocessed clinical samples.
摘要
我们描述了一种电化学类似荧光偏振的方法，该方法可直接在未稀释的血清中定量测量特定蛋白质（趋化因子 IP-10）。该传感器是无标记、免清洗的电子传感器，这表明它可以支持在未经处理的临床样本中进行即时检测诊断蛋白。
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