皮肤利什曼病患者的生活质量。
Quality of life in patients with cutaneous leishmaniasis.
机构信息
Leishmaniasis Research Center, Kerman University of Medical Sciences, Iran.
出版信息
Arch Iran Med. 2013 Aug;16(8):474-7.
BACKGROUND
Leishmaniasis is a zoonotic infection caused by a protozoa belonging to the genus Leishmania. Its clinical manifestations range from a self-healing cutaneous leishmaniasis (CL) to lethal visceral leishmaniasis. We aim to examine the quality of life of patients with CL in Kerman, Iran.
METHODS
In this cross-sectional study we evaluated 124 patients with CL. The Dermatology Life Quality Index (DLQI) questionnaire was used for measuring quality of life. Data on demographics and characteristics of the lesions also were collected. Mann-Whitney U-test and Kruskal-Wallis were used for data analyses.
RESULTS
The mean DLQI score was 5.87 ± 5.96. We observed the highest effect in the symptoms and feelings domains; the lowest effect was seen in the treatment domain of the DLQI. There was no significant difference in DLQI scores between men and women. Patients with ulcerated lesions had lower quality of life (P < 0.05).
CONCLUSION
CL significantly affects the quality of life of patients. Further studies are suggested to examine the effect of its treatment on the quality of life in these patients.
背景
利什曼病是一种由原生动物属利什曼原虫引起的人畜共患病感染。其临床表现从可自行痊愈的皮肤利什曼病（CL）到致命的内脏利什曼病不等。我们旨在研究伊朗克尔曼省 CL 患者的生活质量。
方法
在这项横断面研究中，我们评估了 124 例 CL 患者。使用皮肤病生活质量指数（DLQI）问卷来衡量生活质量。还收集了人口统计学和病变特征的数据。采用曼-惠特尼 U 检验和克鲁斯卡尔-沃利斯检验进行数据分析。
结果
平均 DLQI 评分为 5.87 ± 5.96。我们观察到在症状和感觉领域的影响最大；在 DLQI 的治疗领域影响最小。男女之间的 DLQI 评分无显著差异。有溃疡病变的患者生活质量较低（P < 0.05）。
结论
CL 显著影响患者的生活质量。建议进一步研究以检查其治疗对这些患者生活质量的影响。
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