皮肤利什曼病对患者生活质量的影响。
Effects of cutaneous leishmaniasis on patients' quality of life.
机构信息
Department of Medical Laboratory Science, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
Institute of Biotechnology, Bahir Dar University, Bahir Dar, Ethiopia.
出版信息
BMC Infect Dis. 2024 Jun 18;24(1):598. doi: 10.1186/s12879-024-09518-3.
INTRODUCTION
Cutaneous Leishmaniasis (CL) is caused by protozoan parasite called Leishmania. It is endemic in more than 100 countries globally. Despite its vast prevalence and impact on quality of life, it is one of the most neglected tropical dermatological diseases. The CL burden has often been expressed based on the physical disfigurement caused by the disease. However, considering the impact of the disease beyond physical impairment and changes in patients' appearance would help to better understand the disease as a public health problem. The effect of CL on patients' quality of life was determined in this study.
METHODS
The data that were related to quality of life were collected using Standard one-week Dermatology Life Quality Index (DLQI) questionnaire. The questions were categorized under seven domains: symptoms & feelings, daily activities, work and school, leisure, personal relationships, and treatment. Each question was scored on a three-point scale: Very much (3), A lot (2), A little (1), Undecided (0), and Not at all (0). The sum of the scores lied between 0 and 48. A higher score shows worse quality of life. The data were entered and analysed using Statistical Package for Social Science 23. Frequencies and proportions were used to describe the data. Differences were considered statistically significant at p < 0.05.
RESULTS
The lives of the majority of CL patients (60.7%) were significantly affected by CL. The quality of life of patients was moderately impacted by CL in 25% of the CL patients. In 32.1% of the CL patients, the effect of CL on patients' quality of life was very large. The quality of one CL patient's life was extremely largely affected. The disease had a small effect on 32.1% of the CL patients. Personal relationship was the most affected domain followed by symptoms and feelings and treatment. Future study including rural regions is required.
CONCLUSION
The Dermatology Life Quality Index demonstrates that CL has a small to extremely very large negative effect on the quality of life of patients.
简介
皮肤利什曼病（CL）是由原生动物寄生虫引起的。它在全球 100 多个国家流行。尽管它的发病率很高，对生活质量有很大影响，但它是最被忽视的热带皮肤病之一。CL 的负担通常是根据疾病引起的身体畸形来表达的。然而，考虑到疾病对身体损伤和患者外貌变化以外的影响，将有助于更好地理解这种疾病作为一个公共卫生问题。本研究旨在确定 CL 对患者生活质量的影响。
方法
使用标准的一周皮肤病生活质量指数（DLQI）问卷收集与生活质量相关的数据。问题分为七个领域：症状和感觉、日常活动、工作和学校、休闲、人际关系和治疗。每个问题都在三分制上进行评分：非常多（3）、很多（2）、有点（1）、不确定（0）和一点也不（0）。得分在 0 到 48 之间。得分越高表示生活质量越差。使用社会科学统计软件包 23 输入和分析数据。使用频率和比例描述数据。p 值<0.05 为差异有统计学意义。
结果
大多数 CL 患者（60.7%）的生活受到 CL 的显著影响。CL 对 25%的 CL 患者的生活质量有中度影响。在 32.1%的 CL 患者中，CL 对患者生活质量的影响非常大。一位 CL 患者的生活受到极大影响。疾病对 32.1%的 CL 患者影响较小。人际关系是受影响最严重的领域，其次是症状和感觉以及治疗。需要进行包括农村地区在内的未来研究。
结论
皮肤病生活质量指数表明，CL 对患者的生活质量有小到非常大的负面影响。
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