2009 年，对感染 HIV 的儿童中季节性流感病毒和 H1N1（2009）大流行流感病毒疾病进行的前瞻性队列研究。
Prospective cohort study comparing seasonal and H1N1(2009) pandemic influenza virus illnesses in HIV-infected children during 2009.
机构信息
From the *National Institute of Communicable Diseases-Division of National Health Laboratory Service; †Department of Science and Technology/National Research Foundation: Vaccine Preventable Diseases; ‡Medical Research Council: Respiratory and Meningeal Pathogens Research Unit; and §Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
出版信息
Pediatr Infect Dis J. 2014 Feb;33(2):174-6. doi: 10.1097/INF.0b013e3182a73ebb.
A cohort of 410 young HIV-infected children was prospectively investigated for seasonal and A(H1N1p)2009 influenza virus illness during 2009. The incidence of confirmed illness due to seasonal influenza was 3-fold greater than A(H1N1p)2009 (0.7 vs. 0.2 per 100 child-weeks, respectively; P = 0.0001), and the clinical presentations were similar. Illnesses due to seasonal and A(H1N1p)2009 influenza were self-limiting without neuraminidase inhibitor therapy.
在 2009 年，前瞻性调查了一组 410 名感染 HIV 的年轻儿童，以了解季节性和 A(H1N1p)2009 流感病毒疾病的情况。确诊的季节性流感发病率是 A(H1N1p)2009 的 3 倍（分别为每 100 个儿童周 0.7 例和 0.2 例；P=0.0001），临床表现相似。季节性和 A(H1N1p)2009 流感引起的疾病未经神经氨酸酶抑制剂治疗即可自行缓解。
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