Department of Physical Therapy, Recanati School for Community Health Professions, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Am J Hum Biol. 2013 Sep-Oct;25(5):617-21. doi: 10.1002/ajhb.22420. Epub 2013 Aug 1.
to evaluate the association between 2D:4D finger length ratios (representing the prenatal environment, i.e., early androgen exposure) and reproductive indices, such as age at menarche, menopausal age, and length of reproductive period.
Retrospective data on age at menarche and menopausal age as well as x-rays of both hands were obtained from 674 Chuvashian women aged 18-70 years (mean 46.32 ± 15.42). Finger and metacarpal length ratios as well as visual classification of finger ratio types, were estimated from the x-rays.
We found that a low 2D:4D ratio (radiologically evaluated), a masculine 2D:4D ratio type (visually evaluated), and a putative bioassay for prenatal androgen exposure, were associated with a later menarche and a shorter reproductive period. No association was found with menopausal age.
评估 2D:4D 手指长度比(代表产前环境,即早期雄激素暴露)与生殖指数(如初潮年龄、绝经年龄和生殖期长度)之间的关系。
从 674 名 18-70 岁的楚瓦什女性(平均年龄 46.32±15.42 岁)中获取初潮年龄和绝经年龄的回顾性数据以及双手的 X 射线。从 X 射线中估计手指和掌骨长度比以及手指比率类型的视觉分类。
我们发现,低 2D:4D 比率(放射学评估)、男性 2D:4D 比率类型(视觉评估)和产前雄激素暴露的生物检测与较晚的初潮和较短的生殖期相关。与绝经年龄无关。