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无症状HBsAg携带者尿液中乙肝病毒DNA的检测

[Detection of hepatitis B virus DNA in urine of asymptomatic HBsAg carriers].

作者信息

Dai Z S

机构信息

Department of Epidemiology, First Medical University of PLA, Guangzhou.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 1990 Jun;11(3):138-40.

PMID:2390777
Abstract

Urine samples from 100 asymptomatic HBsAg carriers were examined for HBV DNA by a simple spot hybridization technique. The results showed that the positivity rate of HBV DNA of urine collected from HBsAg carriers with negative HBeAg was 6.5% where as that from HBsAg carriers with positive HBeAg were 21.1%. The above results suggested that presence of HBV in urine may be of important epidemiological significance in the contact transmission of Hepatitis B.

摘要

采用一种简单的斑点杂交技术对100名无症状乙肝表面抗原(HBsAg)携带者的尿液样本进行了乙肝病毒(HBV)DNA检测。结果显示,HBeAg阴性的HBsAg携带者尿液中HBV DNA阳性率为6.5%,而HBeAg阳性的HBsAg携带者尿液中HBV DNA阳性率为21.1%。上述结果表明,尿液中存在HBV可能在乙型肝炎的接触传播中具有重要的流行病学意义。

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