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肥胖症在最低随访 7 年时对单髁膝关节置换术的结果没有不良影响。

Obesity has no adverse effect on the outcome of unicompartmental knee replacement at a minimum follow-up of seven years.

机构信息

CHU Rangueil, Institut de l'Appareil Locomoteur, 1 Avenue Jean Pouilhes, Toulouse, France.

出版信息

Bone Joint J. 2013 Aug;95-B(8):1064-8. doi: 10.1302/0301-620X.95B8.31370.

Abstract

The significance of weight in the indications for unicompartmental knee replacement (UKR) is unclear. Our hypothesis was that weight does not affect the long-term rate of survival of UKRs. We undertook a retrospective study of 212 UKRs at a mean follow-up of 12 years (7 to 22). The patients were distributed according to body mass index (BMI; < vs ≥ 30 kg/m(2)) and weight (< vs ≥ 82 kg). Kaplan-Meier survivorship analysis was performed and ten-year survival rates were compared between the sub-groups. Multimodal regression analysis determined the impact of the various theoretical contraindications on the long-term rate of survival of UKR. The ten-year rates of survival were similar in the two weight subgroups (≥ 82 kg: 93.5% (95% confidence interval (CI) 66.5 to 96.3); < 82 kg: 92.5% (95% CI 82.5 to 94.1)) and also in the two BMI subgroups (≥ 30 kg/m(2): 92% (95% CI 82.5 to 95.3); < 30 kg/m(2): 94% (95% CI 78.4 to 95.9)). Multimodal regression analysis revealed that weight plays a part in reducing the risk of revision with a relative risk of 0.387, although this did not reach statistical significance (p = 0.662). The results relating weight and BMI to the clinical outcome were not statistically significant. Thus, this study confirms that weight does not influence the long-term rate of survival of UKR.

摘要

体重在单髁膝关节置换术(UKR)适应证中的意义尚不清楚。我们的假设是,体重不会影响 UKR 的长期生存率。我们对 212 例 UKR 进行了回顾性研究,平均随访时间为 12 年(7 至 22 年)。根据体重指数(BMI;<30 kg/m2 和≥30 kg/m2)和体重(<82 kg 和≥82 kg)将患者进行分组。进行 Kaplan-Meier 生存分析,并比较亚组之间的十年生存率。多模态回归分析确定了各种理论禁忌症对 UKR 长期生存率的影响。两个体重亚组的十年生存率相似(≥82 kg:93.5%(95%置信区间 66.5 至 96.3);<82 kg:92.5%(95%置信区间 82.5 至 94.1)),两个 BMI 亚组的十年生存率也相似(≥30 kg/m2:92%(95%置信区间 82.5 至 95.3);<30 kg/m2:94%(95%置信区间 78.4 至 95.9))。多模态回归分析显示,体重可降低翻修风险,相对风险为 0.387,但未达到统计学意义(p=0.662)。体重与 BMI 与临床结果的关系无统计学意义。因此,本研究证实体重不会影响 UKR 的长期生存率。

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