Mohammad Hasan R, Matharu Gulraj S, Judge Andrew, Murray David W
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre, Oxford OX3 7LD, United Kingdom; Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, Level 1 Learning and Research Building, Southmead Hospital, Westbury-on-Trym, Bristol BS10 5NB, United Kingdom.
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre, Oxford OX3 7LD, United Kingdom; Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, Level 1 Learning and Research Building, Southmead Hospital, Westbury-on-Trym, Bristol BS10 5NB, United Kingdom.
Knee. 2020 Jun;27(3):993-1002. doi: 10.1016/j.knee.2020.02.008. Epub 2020 Feb 27.
Unicompartmental knee replacement (UKR) offers advantages over total knee replacement but has higher revision rates. New instrumentation known as Microplasty was introduced to address this. The aim was to compare the revision rates of UKRs implanted with Microplasty and traditional instrumentation (Non-Microplasty).
National Joint Registry (NJR) data was used to propensity score match 15,906 UKRs (7953 Microplasty and 7953 Non-Microplasty) for important patient, implant and surgical factors. Implant survival rates were determined using the Kaplan-Meier method and compared using Cox regression models in a multilevel model.
The five-year implant survival for Microplasty and Non-Microplasty UKRs were 96.7% (95% CI: 96.0%-97.2%) and 94.5% (CI: 93.8-95.1%), respectively. The revision rate for Microplasty UKR was significantly lower than that of Non-Microplasty UKRs (hazard ratio [HR] = 0.77, p = 0.008). Compared with Non-Microplasty UKRs, the revision rate of Microplasty UKRs implanted during the year after the introduction of Microplasty was lower, but the difference was not significant (HR: 0.86, CI: 0.67-1.10, p = 0.23), whereas for those implanted more than a year after introduction, the difference was significant (HR: 0.69, CI: 0.54-0.89, p = 0.004).
The use of Microplasty instrumentation has resulted in an improved five-year UKR survival. Microplasty UKR implanted during the first year after introduction had a small, non-significant decrease in revision rate. As the revision rate did not increase, this suggests that there is no adverse learning curve effect. Microplasty UKRs implanted after this transition period had a revision rate 31% lower than the Non-Microplasty group.
II.
单髁膝关节置换术(UKR)相较于全膝关节置换术具有优势,但翻修率较高。为此引入了一种名为Microplasty的新型器械。目的是比较使用Microplasty和传统器械(非Microplasty)植入的UKR的翻修率。
利用国家关节注册中心(NJR)的数据,针对重要的患者、植入物和手术因素,对15906例UKR(7953例使用Microplasty,7953例使用非Microplasty)进行倾向评分匹配。使用Kaplan-Meier方法确定植入物生存率,并在多水平模型中使用Cox回归模型进行比较。
使用Microplasty和非Microplasty的UKR的五年植入物生存率分别为96.7%(95%CI:96.0%-97.2%)和94.5%(CI:93.8-95.1%)。使用Microplasty的UKR的翻修率显著低于使用非Microplasty的UKR(风险比[HR]=0.77,p=0.008)。与使用非Microplasty的UKR相比,在引入Microplasty后的第一年植入的使用Microplasty的UKR的翻修率较低,但差异不显著(HR:0.86,CI:0.67-1.10,p=0.23),而对于在引入一年多后植入的UKR,差异显著(HR:0.69,CI:0.54-0.89,p=0.004)。
使用Microplasty器械提高了UKR的五年生存率。在引入后的第一年植入的使用Microplasty的UKR的翻修率有小幅下降,但不显著。由于翻修率没有增加,这表明不存在不良学习曲线效应。在这个过渡期之后植入的使用Microplasty的UKR的翻修率比非Microplasty组低31%。
II级。