内皮蛋白 C 受体与疟疾。
The endothelial protein C receptor and malaria.
机构信息
University of Amsterdam.
出版信息
Blood. 2013 Aug 1;122(5):624-5. doi: 10.1182/blood-2013-06-508531.
PMID:23908442
Abstract
In this issue of Blood, Moxon et al provide novel insight into the pathogenesis of cerebral malaria, linking loss of the endothelial protein C receptor (EPCR) on brain vessels, caused by cytoadherent infected erythrocytes, with localized coagulation, inflammation, and disruption of endothelial barrier function.
摘要
在本期《Blood》杂志中，Moxon 等人提供了关于脑型疟疾发病机制的新见解，将血管内皮蛋白 C 受体（EPCR）的缺失与局灶性凝血、炎症和内皮屏障功能障碍联系起来，而这种缺失是由黏附在血管上的被感染红细胞引起的。
Zotero 插件