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[循环免疫复合物与重症肌无力(78例分析)]

[Circulating immune complexes and myasthenia gravis (analysis of 78 cases)].

作者信息

Tu L H

机构信息

Changhai Hospital, Shanghai.

出版信息

Zhonghua Shen Jing Jing Shen Ke Za Zhi. 1990 Jun;23(3):130-2, 188.

PMID:2390882
Abstract

For the sake of studying the circulating immune complexes (CIC) of 78 patients with myasthenia gravis (MG), the agglutination assay of C3b sensitized with yeast cell (C3bSYCA) was used. The anti human C3 ELISA was also used for 21 out of the 78 patients. The positive results in the entire group of the patients studied were found to reach 82% and the IgG and IgM CIC were detected also with anti-human C3 ELISA. The titres of CIC thus determined decreased as the clinical conditions improved. It was considered that CIC might be regarded as a referential index to observe the patient's clinical condition and to evaluate the effect of treatment and to identify certain immune aberration of MG as well.

摘要

为研究78例重症肌无力(MG)患者的循环免疫复合物(CIC),采用酵母细胞致敏C3b凝集试验(C3bSYCA)。78例患者中的21例还采用了抗人C3 ELISA法。在所研究的全部患者中,阳性结果达82%,且用抗人C3 ELISA法也检测到了IgG和IgM CIC。如此测定的CIC滴度随临床病情改善而降低。认为CIC可作为观察患者临床病情、评估治疗效果以及识别MG某些免疫异常的参考指标。

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