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利用XIXA对大鼠糖尿病性白内障晶状体锌浓度变化的研究

[Study on change in zinc concentration for diabetic cataractous lenses in rats by means of XIXA].

作者信息

Liu X, Zhang Y, Zhang S, Zhao Q, Zhang Y, Wu L, Jiang J

机构信息

Laboratory of Nuclear Physics, Sichuan University.

出版信息

Hua Xi Yi Ke Da Xue Xue Bao. 1990 Jun;21(2):134-6.

PMID:2391092
Abstract

The SD rats were injected with streptozotocin to induce diabetic cataract. Element Zn as well as K, Ca, Mn, Fe, Cu, Pb, Se, etc. in the eye lenses was determined by means of X-ray induced X-fluorescence analysis (XIXA). Compared to values for normal healthy rats, the concentration of Zn and Fe in the cataractous lenses increased, the concentration of K decreased, and that of the others did not change prominently. The change in Zn concentration was probably to meet the needs of the metabolic adjustment in the eye lenses, which would not be the reason for directly inducing diabetic cataract.

摘要

将链脲佐菌素注射到SD大鼠体内以诱导糖尿病性白内障。通过X射线激发X荧光分析(XIXA)测定晶状体中的锌元素以及钾、钙、锰、铁、铜、铅、硒等元素。与正常健康大鼠的值相比,白内障晶状体中锌和铁的浓度升高,钾的浓度降低,其他元素的浓度没有明显变化。锌浓度的变化可能是为了满足晶状体代谢调节的需要,而这并非直接诱发糖尿病性白内障的原因。

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