Dipartimento di Scienze Sperimentali e Biotecnologie Applicate, Laboratorio di Fisiologia Comparata dell'Esercizio Fisico, Facoltà di Medicina Veterinaria, Università degli Studi di Messina, Polo Universitario Annunziata, 98168 Messina, Italy.
Res Vet Sci. 2013 Dec;95(3):1151-4. doi: 10.1016/j.rvsc.2013.07.005. Epub 2013 Aug 2.
Prothrombin Time (PT), Activated Partial Prothrombin Time (APTT), Fibrinogen concentration (Fbg) and Platelet number (Plt) were evaluated in 20 young athletic horses during a training program. A standardized exercise test (SET) was performed every month for three months. The V4 variations (the speed, in m/min, reached at the blood lactate concentration of 4 mmol/l) obtained for each test were calculated to assess the effect of training program on athletic performance. Blood samples were collected at 20-day intervals over a period of 80 days from the beginning of the training program. The V4 (P < 0.001), PT (P < 0.001), APTT (P < 0.01), Fbg (P < 0.01) and Plt (P < 0.001) varied throughout the training period showing that the modifications of clotting mechanism in response to training period may be considered as a normal physiological response of the hemostatic system to training exercise.
在训练计划期间，对 20 匹年轻运动马的凝血酶原时间 (PT)、活化部分凝血活酶时间 (APTT)、纤维蛋白原浓度 (Fbg) 和血小板数 (Plt) 进行了评估。进行了为期三个月的每月一次的标准化运动测试 (SET)。计算了每次测试获得的 V4 变化（以 m/min 为单位，达到血乳酸浓度为 4 mmol/l 时的速度），以评估训练计划对运动表现的影响。在训练计划开始后的 80 天内，每隔 20 天采集一次血液样本。V4（P<0.001）、PT（P<0.001）、APTT（P<0.01）、Fbg（P<0.01）和 Plt（P<0.001）在整个训练期间发生变化，表明凝血机制的改变是对训练期的反应可能被认为是止血系统对训练运动的正常生理反应。
