Piccione Giuseppe, Bazzano Marilena, Giannetto Claudia, Marafioti Simona, Fazio Francesco
Department of Veterinary Science, University of Messina, Polo Universitario dell'Annunziata, 98168 Messina,
J Vet Sci. 2014;15(1):45-9. doi: 10.4142/jvs.2014.15.1.45. Epub 2013 Oct 18.
The purpose of this study was to investigate the effects of training on prothrombin time, activated partial thromboplastin time, and fibrinogen (Fb) concentrations in horses to assess potential adaptive response to training. Fifteen clinically healthy horses were enrolled in the present study and equally divided into three groups. Group A completed an intense training program, group B participated in a light training program, and group C included sedentary horses. After 5 weeks, group B was subjected to the same training program completed by group A and renamed group B1. Blood samples were collected by jugular venipuncture from each animal at rest and analyzed within 2 h after sampling. A two-way ANOVA for repeated measures showed a significant effect of training (p < 0.05) on Fb concentrations in group B1 alone during the first week after changing the training program. Our findings demonstrated that Fb is a parameter susceptible to training. Fb plasma levels increase with a more intense training program. However, Fb plasma levels decreased after the first week and returned to basel levels, suggesting that the horses had adapted to the new training program.
本研究的目的是调查训练对马的凝血酶原时间、活化部分凝血活酶时间和纤维蛋白原（Fb）浓度的影响，以评估对训练的潜在适应性反应。15匹临床健康的马被纳入本研究，并平均分为三组。A组完成高强度训练计划，B组参加轻度训练计划，C组为久坐不动的马。5周后，B组接受A组完成的相同训练计划，并重新命名为B1组。在每只动物休息时通过颈静脉穿刺采集血样，并在采样后2小时内进行分析。重复测量的双向方差分析显示，在改变训练计划后的第一周，训练对仅B1组的Fb浓度有显著影响（p<0.05）。我们的研究结果表明，Fb是一个易受训练影响的参数。Fb血浆水平随着更强烈的训练计划而增加。然而，Fb血浆水平在第一周后下降并恢复到基线水平，这表明马已经适应了新的训练计划。
