Nyman S, Lang N P, Buser D, Bragger U
School of Dental Medicine, University of Berne, Switzerland.
Int J Oral Maxillofac Implants. 1990 Spring;5(1):9-14.
The biologic principle of guided tissue regeneration was applied to regenerate alveolar bone in conjunction with the placement of titanium dental implants. In one case, complete osseointegration of an implant was achieved by the placement of a Teflon membrane over an implant that had been inserted into an alveolus immediately following tooth extraction. In a second case, the same biologic principle was used to increase the volume (height and width) of a resorbed, edentulous alveolar ridge to provide adequate bone dimensions for implant installation. In both cases, the membranes appear to have prevented the repopulation of the wound area by cells other than those derived from surrounding bone tissue. These two different applications of the principle of guided tissue regeneration open new avenues for reconstructive osseous surgery.
引导组织再生的生物学原理被应用于结合钛牙种植体植入来再生牙槽骨。在一个病例中,通过在拔牙后立即植入牙槽窝的种植体上放置聚四氟乙烯膜,实现了种植体的完全骨整合。在第二个病例中,同样的生物学原理被用于增加吸收后的无牙牙槽嵴的体积(高度和宽度),以提供足够的骨尺寸用于种植体植入。在这两个病例中,膜似乎都阻止了伤口区域被除源自周围骨组织的细胞以外的其他细胞重新占据。引导组织再生原理的这两种不同应用为重建性骨外科手术开辟了新途径。