Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, China.
Analyst. 2013 Oct 7;138(19):5832-8. doi: 10.1039/c3an00914a.
A very simple and versatile polymer assembly approach was developed. We use methoxy-mercapto-poly(ethylene glycol) (mPEG-SH) to conjugate multiple Au shapes to form dense Au monolayer films (MLFs) with 5 nm gaps and generate gigantic enhancement. The results of the discrete dipole approximation (DDA) method to calculate the local electric field distribution of the nanoparticle dimer are in agreement with the experimental data of sensitivity of multiple Au MLFs. 3D Raman spectra, relative standard deviation (RSD) calculation and Raman mapping were used to study the high-reproducibility of the assembled substrate, which is sufficient for trace pesticide residue detection.
我们开发了一种非常简单且通用的聚合物组装方法。我们使用甲氧基巯基聚（乙二醇）（mPEG-SH）将多个 Au 形状连接起来，形成具有 5nm 间隙的密集 Au 单层膜（MLF），并产生巨大的增强效果。离散偶极子近似（DDA）方法计算纳米粒子二聚体的局部电场分布的结果与多 Au MLF 的灵敏度实验数据一致。3D 拉曼光谱、相对标准偏差（RSD）计算和拉曼映射用于研究组装基底的高重现性，这足以用于痕量农药残留检测。
