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透明报告试验至关重要。

Transparent reporting of trials is essential.

机构信息

Centre for Statistics in Medicine, University of Oxford, Oxford, UK.

出版信息

Am J Gastroenterol. 2013 Aug;108(8):1231-5. doi: 10.1038/ajg.2012.457.

Abstract

Reports of randomized controlled trials (RCTs) inform the care of future patients and are especially important to clinicians and systematic reviewers. Readers should satisfy themselves that the study methods were sound. Clinicians should consider the relevance to their own patients, both benefits and harms, and absolute as well as relative effects. Trial reports should provide a clear, transparent, and complete report of what was done and what was found. Unfortunately, bad reporting of RCTs is common, which has serious consequences for clinical practice, research, policy making, and ultimately for patients. RCT reports should adhere to the CONSORT Statement, a minimum set of items that should be addressed. Authors, peer reviewers, and editors should all work to ensure that research reports maximize the value derived from the cost and effort of conducting a trial.

摘要

随机对照试验(RCT)的报告为未来患者的治疗提供信息,对临床医生和系统评价者尤为重要。读者应确保研究方法合理。临床医生应考虑研究结果对自身患者的相关性,包括获益和危害,以及绝对和相对效果。试验报告应清晰、透明、完整地报告所做的工作和发现的结果。不幸的是,RCT 的报告质量普遍较差,这对临床实践、研究、决策制定,最终对患者都产生了严重后果。RCT 报告应遵循 CONSORT 声明,这是应解决的最小项目集。作者、同行评审者和编辑都应努力确保研究报告最大限度地提高从试验成本和努力中获得的价值。

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