Formerly Department of Neurology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey.
J Clin Neurophysiol. 2013 Aug;30(4):357-61. doi: 10.1097/WNP.0b013e31829d75db.
Attention deficit hyperactivity disorder is a syndrome of unknown etiology that affects 3% to 7% of the population. Although no objective test exists to support the diagnosis, EEG discharges related to the neuropsychiatric abnormalities have a high incidence in attention deficit hyperactivity disorder. The aim of this study was to elucidate the quantitative and qualitative characteristics of EEG abnormality in attention deficit hyperactivity disorder. Nonrapid eye movement sleep EEGs were evaluated in 134 patients with attention deficit hyperactivity disorder in terms of age, EEG timing, spike and wave index, foci, and seizures. All patients had spike and wave paroxysms that changed with age at and time to first EEG. Only half of the patients had seizures and 46 patients had neither seizures nor foci. Thirty-eight patients had the EEG findings of benign focal epilepsy of childhood. Our data support the view that spike and wave activity evolves in time and that EEG discharges are related to neuropsychiatric symptoms even when a diagnosable seizure disorder is absent.
注意缺陷多动障碍是一种病因不明的综合征，影响人群的 3%至 7%。尽管没有客观的测试来支持诊断，但与神经精神异常相关的 EEG 放电在注意缺陷多动障碍中发生率很高。本研究旨在阐明注意缺陷多动障碍中 EEG 异常的定量和定性特征。对 134 例注意缺陷多动障碍患者的非快速眼动睡眠 EEG 进行了评估，涉及年龄、EEG 时间、棘波和尖波指数、病灶和癫痫发作。所有患者均有棘波和尖波发作，其出现的年龄和首次 EEG 的时间均随年龄而变化。只有一半的患者有癫痫发作，46 例患者既没有癫痫发作也没有病灶。38 例患者的脑电图表现为良性儿童局灶性癫痫。我们的数据支持这样一种观点，即棘波和尖波活动随时间演变，并且 EEG 放电与神经精神症状有关，即使不存在可诊断的癫痫发作障碍。
