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一期吻合加预防性造口术与 Hartmann 手术治疗穿孔性憩室炎的对比——造口还纳率的比较。

Primary anastomosis with a defunctioning stoma versus Hartmann's procedure for perforated diverticulitis--a comparison of stoma reversal rates.

机构信息

Department of General, Visceral and Transplantation Surgery, RWTH Aachen University Hospital, Pauwelsstr. 30, 52074, Aachen, Germany,

出版信息

Int J Colorectal Dis. 2013 Dec;28(12):1681-8. doi: 10.1007/s00384-013-1753-2. Epub 2013 Aug 3.

Abstract

PURPOSE

The ideal treatment of patients with perforated diverticulitis is still controversial. Hartmann's procedure has been the treatment of choice for decades, but primary anastomosis with a defunctioning stoma has become an accepted alternative. The aim of this study was to evaluate the stoma reversal rates after these two surgical strategies.

METHODS

A retrospective review of the data from patients with perforated sigmoid diverticulitis between 2002 and 2011 undergoing a Hartmann's procedure (HP) versus a primary anastomosis with a defunctioning stoma (PA) was performed. Additionally, patients were contacted by mail or telephone in March 2012 using a standardized questionnaire.

RESULTS

A total of 98 patients were identified: 72 undergoing HP and 26 patients receiving PA. The median follow-up time was 63 months (range 4-118). Whilst 85 % of patients with PA have had their stoma reversed, only 58 % of patients with an HP had a stoma reversal (p = 0.046). The median period until stoma reversal was significantly longer for HP (19 weeks) than for PA (12 weeks; p = 0.03). The 30-day mortality for PA was 12 % as opposed to 25 % for HP (p = 0.167). According to the Clavien-Dindo classification, surgical complications occurred significantly less frequently in patients with PA (p = 0.014).

CONCLUSION

The stoma reversal rates for PA are significantly higher than for HP. Thus, depending on the overall clinical situation, primary resection and anastomosis with a proximal defunctioning stoma might be the optimal procedure for selected patients with perforated diverticular disease.

摘要

目的

对于穿孔性憩室炎患者的理想治疗方法仍存在争议。几十年来,Hartmann 手术一直是首选治疗方法,但带预防性造口的一期吻合术已成为一种公认的替代方法。本研究旨在评估这两种手术策略后的造口逆转率。

方法

回顾性分析 2002 年至 2011 年间接受 Hartmann 手术(HP)与带预防性造口的一期吻合术(PA)治疗的穿孔性乙状结肠憩室炎患者的数据。此外,于 2012 年 3 月使用标准化问卷通过邮件或电话联系患者。

结果

共确定了 98 例患者:72 例行 HP,26 例行 PA。中位随访时间为 63 个月(范围 4-118)。虽然 85%的 PA 患者已行造口逆转,但只有 58%的 HP 患者行造口逆转(p=0.046)。HP 患者行造口逆转的中位时间明显长于 PA(19 周比 12 周;p=0.03)。PA 的 30 天死亡率为 12%,而 HP 为 25%(p=0.167)。根据 Clavien-Dindo 分类,PA 患者的手术并发症发生率明显低于 HP(p=0.014)。

结论

PA 的造口逆转率明显高于 HP。因此,根据整体临床情况,对于穿孔性憩室炎患者,带预防性造口的一期切除术和吻合术可能是一种优化的选择。

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