Department of Surgery, Erasmus University Hospital, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
J Gastrointest Surg. 2010 Apr;14(4):651-7. doi: 10.1007/s11605-010-1155-5. Epub 2010 Feb 2.
The existing literature regarding acute perforated diverticulitis only reports about short-term outcome; long-term following outcomes have not been assessed before. The aim of this study was to assess long-term quality of life (QOL) after emergency surgery for perforated diverticulitis.
Validated QOL questionnaires (EQ-VAS, EQ-5D index, QLQ-C30, and QLQ-CR38) were sent to all eligible patients who had undergone emergency surgery for perforated diverticulitis in five teaching hospitals between 1990 and 2005. Differences were compared between patients that had undergone Hartmann's procedure (HP) or resection with primary anastomosis (PA) and also compared to a sex- and age-matched sample of healthy subjects.
Of a total of 340 patients, only 150 patients (44%) were found still alive in July 2007 (median follow-up 71 months). The response rate was 87%. In patients with PA, QOL was similar to the general population, whereas QOL after HP was significantly lower. The presence of a stoma was found to be an independent factor related to worse QOL. The deterioration in QOL was mainly due to problems in physical function and body image.
Survivors after perforated diverticulitis had a worse QOL than the general population, which was mainly due to the presence of an end colostomy. QOL may improve if these stomas are reversed or not be performed in the first place.
现有的关于急性穿孔性憩室炎的文献仅报告了短期结果;之前尚未评估长期随访结果。本研究旨在评估因穿孔性憩室炎而行急诊手术后的长期生活质量(QOL)。
向 1990 年至 2005 年间在五所教学医院接受穿孔性憩室炎急诊手术的所有符合条件的患者发送了经过验证的 QOL 问卷(EQ-VAS、EQ-5D 指数、QLQ-C30 和 QLQ-CR38)。比较了接受 Hartmann 手术(HP)或一期吻合切除术(PA)的患者之间的差异,并与性别和年龄匹配的健康人群进行了比较。
在总共 340 名患者中,只有 150 名患者(44%)在 2007 年 7 月仍然存活(中位随访 71 个月)。应答率为 87%。在接受 PA 的患者中,QOL 与普通人群相似,而接受 HP 的患者 QOL 明显较低。存在造口是与较差 QOL 相关的独立因素。QOL 的恶化主要归因于身体功能和身体形象问题。
穿孔性憩室炎幸存者的生活质量比普通人群差,这主要是由于存在结肠造口。如果这些造口被逆转或首先不进行,QOL 可能会改善。